# UMF Honey Association Incorporated
> This is the official portal of the account "UMF Honey Association Incorporated", built and managed using Brandkit.
It provides content, product information, and resources tailored for UMF Honey Association Incorporated's audience.
## Pages
- [Calculator | UMF](https://umf.brandkitapp.com/calculator)
- [Wound Care | UNF Honey Association](https://umf.brandkitapp.com/wound-care): Would care research from the UMF Honey Association
## Archives
- [WMHD Logo Suite](https://umf.brandkitapp.com/asset-page/787163-wmhd-logo-suite)
## Documents
- [Member Manual June 2026](https://umf.brandkitapp.com/asset-page/869701-member-manual-june-2026) : This manual has been developed to support you as a UMF™ licence holder by clearly explaining how the UMF™ system operates, what membership means in day-to-day practice, and the collective responsibilities we all share in protecting the value, credibility, and reputation of the UMF™ trademark.
- [Member Manual](https://umf.brandkitapp.com/asset-page/843131-member-manual) 
- [In Vitro Evidence for the Efficacy of Manuka Honey and Its pharmaceuticals-18-00534](https://umf.brandkitapp.com/asset-page/800906-in-vitro-evidence-for-the-efficacy-of-manuka-honey-and-its-pharmaceuticals-18-00534) : Background/Objectives: While various clinical manifestations occur in sporotrichosis, cutaneous forms predominate. The recommended sporotrichosis treatment is itraconazole, an antifungal with certain restrictions. In recent years, the observation of reduced treatment effectiveness in some patients has arisen, possibly due to Sporothrix spp. resistance mechanisms. Consequently, there is a growing need for alternative therapeutic approaches. This study investigates the antifungal activity of manuka honey (MH) against pathogenic species of the genus Sporothrix. Methods: In this study, we assessed MH antifungal efficacy across concentrations ranging from 5% to 40% against 26 Sporothrix spp. isolates. In addition, its components were evaluated through chromatography and other in vitro techniques. Results: Minimum inhibitory concentrations of MH were found to be 15–40%, 10–15%, and 5–10% for Sporothrix brasiliensis, Sporothrix schenckii, and Sporothrix globosa, respectively. Purified methylglyoxal did not hinder Sporothrix growth. The MH antifungal potential was compromised through treatment with catalase or filtration through a 0.22 m cellulose membrane. Chromatographic analysis of the volatile organic compounds (VOCs) present in MH identified 40 VOCs, including carbonyl compounds, alcohols, esters, aromatic hydrocarbons, heterocyclic compounds, terpenoids, and carboxylic acids. Additionally, two phenolic compounds were identified as potential markers for the authentication of MH, along with a disaccharide that may contribute to its antifungal activity. Conclusions: MH has demonstrated biological activity against the most significant Sporothrix species with pathogenic impact on humans. This suggests its consideration in future research endeavors focused on novel topical treatments for cutaneous sporotrichosis in both human and animal subjects.
- [Medical-grade honey has superior antibacterial properties against common bacterial wound isolates in cats and dogs](https://umf.brandkitapp.com/asset-page/800903-medical-grade-honey-has-superior-antibacterial-properties-against-common-bacterial-wound-isolates-in-cats-and-dogs) 
- [Manuka honey as a non-antibiotic alternative against Staphylococcus spp. and their small colony variant (SCVs) phenotypes 2025](https://umf.brandkitapp.com/asset-page/800905-manuka-honey-as-a-non-antibiotic-alternative-against-staphylococcus-spp-and-their-small-colony-variant-scvs-phenotypes-2025) : Onyango LA and Liang J (2024) Manuka honey as a non-antibiotic alternative against Staphylococcus spp. and their small colony variant (SCVs) phenotypes. Front. Cell. Infect. Microbiol. 14:1380289
- [Manuka Honey why this multi action antimicrobial is a valid alternative to silver](https://umf.brandkitapp.com/asset-page/800904-manuka-honey-why-this-multi-action-antimicrobial-is-a-valid-alternative-to-silver) 
- [Comparative study of the antibacterial activity of Algerian honeys and Manuka honey toward pathogenic bacteria from burn wound infections](https://umf.brandkitapp.com/asset-page/800908-comparative-study-of-the-antibacterial-activity-of-algerian-honeys-and-manuka-honey-toward-pathogenic-bacteria-from-burn-wound-infections) : Presently, most of the reported infections are of a bacterial origin; however, this leads to a limit within the literature and research around infections caused by fungal pathogens, which are now developing resistance to antibiotic medicines. Of the natural antimicrobial agents, honey has been observed with demonstrable and highly exploitable antimicrobial and infection control related to wound healing properties; therefore, it has been incorporated into many standard pharmaceutical formulations. Generally, these products utilize a pure sample of honey as a bioactive ingredient in a product which has been purposely designed for the convenience of application. This article aims to review information available from published reports on various bioactivities of a variety of medical-grade honey products, including manuka and other conventional non-manuka types sourced from different floral types and geographical regions. Additionally, this review highlights the antibiotic activities of various types of honey products tested against pathogenic strains of bac-teria, yeast and fungi, and their applications in the formulation of healthcare products.
- [Honey as A Natural Anti microbial](https://umf.brandkitapp.com/asset-page/800907-honey-as-a-natural-anti-microbial) : Honey, a natural product with a rich history of medicinal use, has gained increasing recognition for its potent antimicrobial properties, particularly against antibiotic-resistant pathogens. This review focuses on the antimicrobial mechanisms of honey, including its efficacy against resistant bacteria, such as Methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. The antimicrobial action of honey is multifactorial, involving hydrogen peroxide production, phenolic compounds, high sugar concentrations, and the presence of bee defensin-1. The composition of honey varies based on its floral source, which can influence its antimicrobial strength. Certain types, such as Manuka honey, are particularly effective in clinical applications due to their higher levels of bioactive compounds. Honey has also been shown to disrupt bacterial biofilms, a major factor in antibiotic resistance, enhancing its therapeutic potential in treating chronic wounds and infections, especially in patients with compromised immune systems. Moreover, honey’s ability to improve wound healing, reduce inflammation, and promote tissue regeneration highlights its broad therapeutic profile. As antibiotic resistance continues to challenge modern healthcare, honey offers a promising complementary treatment in antimicrobial therapy. Research into its specific bioactive components and potential synergistic effects with other natural agents, like ginger and propolis, could expand its applications. Standardizing honey products for medical use and establishing clinical guidelines are essential for optimizing its therapeutic benefits. As scientific understanding of honey’s antimicrobial mechanisms deepens, its integration into healthcare systems as an adjunct therapy is expected to increase, offering a natural and effective alternative in the fight against infectious diseases.
- [UMFHA Discovery Pack Oct 25](https://umf.brandkitapp.com/asset-page/790151-umfha-discovery-pack-oct-25) 
- [Brandkit Login](https://umf.brandkitapp.com/asset-page/776994-brandkit-login) 
- [Honey used as an ingredient (002).pdf Notice](https://umf.brandkitapp.com/asset-page/758844-honey-used-as-an-ingredient-002pdf-notice) 
- [2016-05-02 Notice regarding subcontracting](https://umf.brandkitapp.com/asset-page/758843-2016-05-02-notice-regarding-subcontracting) 
- [2015-02-19 Notice regarding claims](https://umf.brandkitapp.com/asset-page/758836-2015-02-19-notice-regarding-claims) 
- [2018-07-30 Notification re mono and multi decision](https://umf.brandkitapp.com/asset-page/758841-2018-07-30-notification-re-mono-and-multi-decision) 
- [2022-04-01 Notice re UMFHA Annual Membership, Licence Fee and Levy Increase](https://umf.brandkitapp.com/asset-page/758838-2022-04-01-notice-re-umfha-annual-membership-licence-fee-and-levy-increase) 
- [2021-12-02 Notice re Brand Guidlines](https://umf.brandkitapp.com/asset-page/758839-2021-12-02-notice-re-brand-guidlines) 
- [2020-8-17 Notice re Australian Honey v2](https://umf.brandkitapp.com/asset-page/758840-2020-8-17-notice-re-australian-honey-v2) 
- [2016-10-11 Notice release document](https://umf.brandkitapp.com/asset-page/758842-2016-10-11-notice-release-document) 
- [UMF Banners 1 and 2](https://umf.brandkitapp.com/asset-page/758832-umf-banners-1-and-2) 
- [Trade Show Handout](https://umf.brandkitapp.com/asset-page/758828-trade-show-handout) 
- [UMF Banner 3](https://umf.brandkitapp.com/asset-page/758831-umf-banner-3) 
- [Global Honey Research Unit Poster](https://umf.brandkitapp.com/asset-page/758827-global-honey-research-unit-poster) 
- [Expo Table Top Honey Unit Poster](https://umf.brandkitapp.com/asset-page/758826-expo-table-top-honey-unit-poster) 
- [UMF™ Manuka Health Research Summary Aug 2025](https://umf.brandkitapp.com/asset-page/758833-umf-manuka-health-research-summary-aug-2025) 
- [Investigation of the methylglyoxal scavenging kinetics of different food matrices under simulated intestinal conditions](https://umf.brandkitapp.com/asset-page/751061-investigation-of-the-methylglyoxal-scavenging-kinetics-of-different-food-matrices-under-simulated-intestinal-conditions) : This study aimed to evaluate the potential roles of different foods to scavenge exogenous dicarbonyl compounds under simulated gastrointestinal conditions.
- [2021-12-02 Visual Brand Guidelines](https://umf.brandkitapp.com/asset-page/749075-2021-12-02-visual-brand-guidelines) 
- [2021-12-02 UMFHA Brand Guidelines](https://umf.brandkitapp.com/asset-page/749076-2021-12-02-umfha-brand-guidelines) 
- [Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal? ](https://umf.brandkitapp.com/asset-page/748909-immunometabolism-and-the-modulation-of-immune-responses-and-host-defense-a-role-for-methylglyoxal) : In small amounts MGO might boost immune defense and help heal infections.
- [Identification of a Novel Glycoside Leptosin as a Chemical Marker of Manuka Honey](https://umf.brandkitapp.com/asset-page/748510-identification-of-a-novel-glycoside-leptosin-as-a-chemical-marker-of-manuka-honey) : Kato et. al., Identification of a Novel Glycoside Leptosin as a Chemical Marker of Manuka Honey, 2012
- [Mānuka honey-derived methylglyoxal enhances microbial sensing by mucosal-associated invariant T cells](https://umf.brandkitapp.com/asset-page/748508-manuka-honey-derived-methylglyoxal-enhances-microbial-sensing-by-mucosal-associated-invariant-t-cells) 
- [USA manuka brochure](https://umf.brandkitapp.com/asset-page/739725-usa-manuka-brochure) 
- [POSTCARD FINAL](https://umf.brandkitapp.com/asset-page/739724-postcard-final) 
- [USA Manuka Brochure](https://umf.brandkitapp.com/asset-page/726053-usa-manuka-brochure) 
- [A5 One pager on UMF™ Manuka Honey Certification](https://umf.brandkitapp.com/asset-page/726052-a5-one-pager-on-umf-manuka-honey-certification) 
- [Health Science Reports - 2025 - Karami - The Effect of Honey Supplementation on Skeletal MuscleRelated Inflammatory](https://umf.brandkitapp.com/asset-page/724862-health-science-reports-2025-karami-the-effect-of-honey-supplementation-on-skeletal-musclerelated-inflammatory) 
- [USA Dietitian Manuka Brochure](https://umf.brandkitapp.com/asset-page/723359-usa-dietitian-manuka-brochure) 
- [A5 Simple One Pager - UMF the Gold Standard](https://umf.brandkitapp.com/asset-page/723358-a5-simple-one-pager-umf-the-gold-standard) : A simple handout explaining what UMF is.
- [The Potential of Honey as a Prebiotic Food to Re-engineer the Gut Microbiome Toward a Healthy State](https://umf.brandkitapp.com/asset-page/706964-the-potential-of-honey-as-a-prebiotic-food-to-re-engineer-the-gut-microbiome-toward-a-healthy-state) 
- [A-guide-to-NZ-Honey-Labelling](https://umf.brandkitapp.com/asset-page/703491-a-guide-to-nz-honey-labelling) 
- [MENV1002 Info Sheets AW ClimateChange_V3](https://umf.brandkitapp.com/asset-page/691270-menv1002-info-sheets-aw-climatechange_v3) 
- [April 2023 Aotearoa Agri Climate Scenarios](https://umf.brandkitapp.com/asset-page/691271-april-2023-aotearoa-agri-climate-scenarios) 
- [Aotearoa Agriculture Sector Climate Change Roadmap Report](https://umf.brandkitapp.com/asset-page/691272-aotearoa-agriculture-sector-climate-change-roadmap-report) 
- [2024 The Aotearoa Circle Report Protecting New Zealands competitive advantage](https://umf.brandkitapp.com/asset-page/691273-2024-the-aotearoa-circle-report-protecting-new-zealands-competitive-advantage) 
- [Manuka Honey: A Potent Cariostatic Agent— An in vitro Study](https://umf.brandkitapp.com/asset-page/668659-manuka-honey-a-potent-cariostatic-agent-an-in-vitro-study) 
- [Effect of honey in improving the gut microbial balance](https://umf.brandkitapp.com/asset-page/668658-effect-of-honey-in-improving-the-gut-microbial-balance) 
- [High-throughput microbial bioassays to screen potential New Zealand functional food ingredients intended to manage the growth of probiotic and pathogenic gut bacteria](https://umf.brandkitapp.com/asset-page/668656-high-throughput-microbial-bioassays-to-screen-potential-new-zealand-functional-food-ingredients-intended-to-manage-the-growth-of-probiotic-and-pathogenic-gut-bacteria) 
- [Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers](https://umf.brandkitapp.com/asset-page/668634-manuka-honey-impregnated-dressings-in-the-treatment-of-neuropathic-diabetic-foot-ulcers) 
- [Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains with different biofilm-forming abilities](https://umf.brandkitapp.com/asset-page/668630-manuka-type-honeys-can-eradicate-biofilms-produced-by-staphylococcus-aureus-strains-with-different-biofilm-forming-abilities) 
- [Honey: An immunomodulator in wound healing](https://umf.brandkitapp.com/asset-page/668631-honey-an-immunomodulator-in-wound-healing) 
- [In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles](https://umf.brandkitapp.com/asset-page/668632-in-vitro-antiviral-activity-of-honey-against-varicella-zoster-virus-vzv-a-translational-medicine-study-for-potential-remedy-for-shingles) 
- [Anti-influenza Viral Effects of Honey In Vitro: Potent High Activity of Manuka Honey](https://umf.brandkitapp.com/asset-page/668633-anti-influenza-viral-effects-of-honey-in-vitro-potent-high-activity-of-manuka-honey) 
- [Multicentre prospective observational study on professional wound care using honey (Medihoney™)](https://umf.brandkitapp.com/asset-page/668628-multicentre-prospective-observational-study-on-professional-wound-care-using-honey-medihoney) 
- [Antibacterial_substances_in_honey](https://umf.brandkitapp.com/asset-page/668627-antibacterial_substances_in_honey) 
- [Antibacterial activity of varying UMF-graded Manuka honeys](https://umf.brandkitapp.com/asset-page/668624-antibacterial-activity-of-varying-umf-graded-manuka-honeys) 
- [Therapeutic Manuka Honey: No Longer So Alternative](https://umf.brandkitapp.com/asset-page/668625-therapeutic-manuka-honey-no-longer-so-alternative) 
- [Honey in dermatology and skin care: a review](https://umf.brandkitapp.com/asset-page/668626-honey-in-dermatology-and-skin-care-a-review) 
- [The super-food Manuka honey, a comprehensive review of its analysis and authenticity approaches](https://umf.brandkitapp.com/asset-page/668623-the-super-food-manuka-honey-a-comprehensive-review-of-its-analysis-and-authenticity-approaches) 
- [The Use Of Manuka Honey: to promote wound healing](https://umf.brandkitapp.com/asset-page/668622-the-use-of-manuka-honey-to-promote-wound-healing) 
- [Honey for wound care in the 21st century](https://umf.brandkitapp.com/asset-page/668621-honey-for-wound-care-in-the-21st-century) 
- [The super-food Manuka honey, a comprehensive review of its analysis and authenticity approaches](https://umf.brandkitapp.com/asset-page/668620-the-super-food-manuka-honey-a-comprehensive-review-of-its-analysis-and-authenticity-approaches) 
- [In vivo absorption and metabolism of leptosperin and methyl syringate, abundantly present in manuka honey](https://umf.brandkitapp.com/asset-page/668618-in-vivo-absorption-and-metabolism-of-leptosperin-and-methyl-syringate-abundantly-present-in-manuka-honey) 
- [Activities of Manuka Honey](https://umf.brandkitapp.com/asset-page/657167-activities-of-manuka-honey) 
- [Guidance-for-Industry, Proper-Labeling-of-Honey-and-Honey-Products](https://umf.brandkitapp.com/asset-page/653661-guidance-for-industry-proper-labeling-of-honey-and-honey-products) 
- [UMF Brochure](https://umf.brandkitapp.com/asset-page/653656-umf-brochure) 
- [UMF Logo Certified](https://umf.brandkitapp.com/asset-page/652678-umf-logo-certified) 
- [UMF_Double pager_4_Italian](https://umf.brandkitapp.com/asset-page/651088-umf_double-pager_4_italian) 
- [UMF-Double pager_4_Arabic](https://umf.brandkitapp.com/asset-page/651087-umf-double-pager_4_arabic) 
- [UMF_Double pager_4_Indonesian](https://umf.brandkitapp.com/asset-page/651089-umf_double-pager_4_indonesian) 
- [UMF Double pager 4 MAR23 DEDE](https://umf.brandkitapp.com/asset-page/651085-umf-double-pager-4-mar23-dede) 
- [UMF Double pager-4_French](https://umf.brandkitapp.com/asset-page/651082-umf-double-pager-4_french) 
- [UMF Double pager 4 MAR23 JAJP](https://umf.brandkitapp.com/asset-page/651084-umf-double-pager-4-mar23-jajp) 
- [UMF Double pager 4 MAR23 Chinese Simplified ZHCN](https://umf.brandkitapp.com/asset-page/651083-umf-double-pager-4-mar23-chinese-simplified-zhcn) 
- [UMF_Double pager_4_MAR22](https://umf.brandkitapp.com/asset-page/651081-umf_double-pager_4_mar22) 
- [Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models](https://umf.brandkitapp.com/asset-page/650387-manuka-honey-inhibits-human-breast-cancer-progression-in-preclinical-models) 
- [Bee-products-as-a-source-of-promising-therapeutic-and-chemoprophylaxis-strategies-against-COVID-19](https://umf.brandkitapp.com/asset-page/558141-bee-products-as-a-source-of-promising-therapeutic-and-chemoprophylaxis-strategies-against-covid-19) 
- [Anti-influenza-Viral-Effects-of-Honey](https://umf.brandkitapp.com/asset-page/558143-anti-influenza-viral-effects-of-honey) 
- [2017_APNZ_Conference_Leptospermum honeys show anti-inflammatory activity presentation](https://umf.brandkitapp.com/asset-page/558144-2017_apnz_conference_leptospermum-honeys-show-anti-inflammatory-activity-presentation) 
- [Anti-influenza-Viral-Effects-of-Honey-In-Vitro](https://umf.brandkitapp.com/asset-page/558142-anti-influenza-viral-effects-of-honey-in-vitro) 
- [Medihoney Barrier Cream, British Journal of Community Nursing, Tissue Viability Supplement](https://umf.brandkitapp.com/asset-page/558140-medihoney-barrier-cream-british-journal-of-community-nursing-tissue-viability-supplement) 
- [Therapeutic Manuka No Longer So Alternative](https://umf.brandkitapp.com/asset-page/558139-therapeutic-manuka-no-longer-so-alternative) 
- [Integra (Dermasciences) Barrier Cream Int A4](https://umf.brandkitapp.com/asset-page/558138-integra-dermasciences-barrier-cream-int-a4) 
## External Links
- [
Mānuka honey-derived methylglyoxal enhances microbial sensing by mucosal-associated invariant T cells - Food & Function (RSC Publishing)
](https://umf.brandkitapp.com/asset-page/758834-manuka-honey-derived-methylglyoxal-enhances-microbial-sensing-by-mucosal-associated-invariant-t-cells-food-amp-function-rsc-publishing) : Methylglyoxal (MGO) is the main antimicrobial determinant associated with using Mānuka Honey as a topical dressing. While direct mechanisms of Mānuka honey MGO's antimicrobial activity have been demonstrated, such as disruption of bacterial fimbria and flagella, no interaction of Mānuka honey-derived MGO wit Food & Function Recent Open Access Articles
- [Mānuka Honey from New Zealand – Good from the Outside In | UMF™](https://umf.brandkitapp.com/asset-page/731036-manuka-honey-from-new-zealand-good-from-the-outside-in-umf) : Mānuka Honey from New Zealand – Good from the Outside In | UMF™
- [
The Potential use of Honey as a Remedy for Allergic Diseases: A Mini Review - PMC
](https://umf.brandkitapp.com/asset-page/724863-the-potential-use-of-honey-as-a-remedy-for-allergic-diseases-a-mini-review-pmc): Honey has been conventionally consumed as food. However, its therapeutic properties have also gained much attention due to its application as a traditional medicine. Therapeutic properties of honey such as anti-microbial, anti-inflammatory, ...
- [Frontiers | Characterization of immunomodulatory responses induced by manuka honey](https://umf.brandkitapp.com/asset-page/720666-frontiers-characterization-of-immunomodulatory-responses-induced-by-manuka-honey) : Manuka honey (MH) is known for its wound-healing, anti-microbial, anti-oxidant and anti-tumor properties. However, there is conflicting evidence regarding th...
- [Effect of Oral Honey Consumption on Immune Function Following Ex-Vivo Lipopolysaccharide Stimulation in Healthy Humans](https://umf.brandkitapp.com/asset-page/720665-effect-of-oral-honey-consumption-on-immune-function-following-ex-vivo-lipopolysaccharide-stimulation-in-healthy-humans)
- [Mānuka Honey’s Immune System Support: A Gentle Nudge | UMF™](https://umf.brandkitapp.com/asset-page/720664-manuka-honeys-immune-system-support-a-gentle-nudge-umf) : Mānuka Honey’s Immune System Support: A Gentle Nudge | UMF™
- [Characterization of immunomodulatory responses induced by manuka honey](https://umf.brandkitapp.com/asset-page/720663-characterization-of-immunomodulatory-responses-induced-by-manuka-honey) : Manuka honey (MH) is known for its wound-healing, anti-microbial, anti-oxidant and anti-tumor properties. However, there is conflicting evidence regarding th...
- [Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria - PubMed](https://umf.brandkitapp.com/asset-page/714017-influence-of-dietary-factors-on-helicobacter-pylori-and-caga-seroprevalence-in-bulgaria-pubmed) : The aim of this study was to assess the association between some dietary factors and prevalence of H. pylori infection or strain virulence in 294 adult asymptomatic blood donors. Methods. Seroprevalence was evaluated using ELISA. Logistic regression was used. Results. Anti-H. …
- [
The Potential of Honey as a Prebiotic Food to Re-engineer the Gut Microbiome Toward a Healthy State - PMC
](https://umf.brandkitapp.com/asset-page/714016-the-potential-of-honey-as-a-prebiotic-food-to-re-engineer-the-gut-microbiome-toward-a-healthy-state-pmc): Honey has a long history of use for the treatment of digestive ailments. Certain honey types have well-established bioactive properties including antibacterial and anti-inflammatory activities. In addition, honey contains non-digestible ...
- [Sensory, Microbiological and Physicochemical Characterisation of Functional Manuka Honey Yogurts Containing Probiotic Lactobacillus reuteri DPC16](https://umf.brandkitapp.com/asset-page/714015-sensory-microbiological-and-physicochemical-characterisation-of-functional-manuka-honey-yogurts-containing-probiotic-lactobacillus-reuteri-dpc16) : Consumer acceptance of synbiotics, which are synergistic combinations of probiotics and their prebiotic substrates, continues to expand in the functional food category. This research aimed at evaluating the effect of antibacterial manuka honey on the probiotic growth and sensory characteristics of potentially synbiotic yogurts manufactured with Lactobacillus reuteri DPC16. Probiotic viable count in yogurts with 5% w/v Manuka honey (Blend, UMFTM 18+, AMFTM 15+ and AMFTM 20+) was evaluated by the spread plate method over the refrigerated storage period of three weeks. A panel of 102 consumers preferred the yogurt made with invert syrup over the manuka honey variants, and the unsweetened control was least liked overall. Invert syrup yogurt was also the most effective in promoting the growth of the probiotic lactobacilli. However, the honey-sweetened yogurts had a more favourable fermentation metabolite profile, especially the lactic and propionic acids, as estimated by nuclear magnetic resonance (NMR) analyses. The probiotic counts in AMFTM 15+ manuka honey yogurt (7 log cfu/mL) were significantly higher than the other honey yogurt types (Manuka Blend and UMFTM 18+) and above the recommended threshold levels. The combination thus can be developed as a synbiotic functional food by further improving the sensory and physicochemical properties such as texture, apparent viscosity and water holding capacity.
- [Effect of honey in improving the gut microbial balance](https://umf.brandkitapp.com/asset-page/714014-effect-of-honey-in-improving-the-gut-microbial-balance)
- [Oligosaccharides Isolated from MGO™ Manuka Honey Inhibit the Adhesion of Pseudomonas aeruginosa, Escherichia Coli O157:H7 and Staphylococcus Aureus to Human HT-29 cells - PubMed](https://umf.brandkitapp.com/asset-page/714013-oligosaccharides-isolated-from-mgo-manuka-honey-inhibit-the-adhesion-of-pseudomonas-aeruginosa-escherichia-coli-o157h7-and-staphylococcus-aureus-to-human-ht-29-cells-pubmed) : Historically, honey is known for its anti-bacterial and anti-fungal activities and its use for treatment of wound infections. Although this practice has been in place for millennia, little information exists regarding which manuka honey components contribute to the protective nature of this product. …
- [Susceptibility of Helicobacter pylori to the antibacterial activity of manuka honey - PubMed](https://umf.brandkitapp.com/asset-page/714012-susceptibility-of-helicobacter-pylori-to-the-antibacterial-activity-of-manuka-honey-pubmed) : Honey is a traditional remedy for dyspepsia, and is still used for this by some medical practitioners although there is no rational basis for its use. The finding that Helicobacter pylori is probably the causative agent in many cases of dyspepsia has raised the possibility that the therapeutic actio …
- [
Oligosaccharides Isolated from MGO™ Manuka Honey Inhibit the Adhesion of Pseudomonas aeruginosa, Escherichia Coli O157:H7 and Staphylococcus Aureus to Human HT-29 cells - PMC
](https://umf.brandkitapp.com/asset-page/706963-oligosaccharides-isolated-from-mgo-manuka-honey-inhibit-the-adhesion-of-pseudomonas-aeruginosa-escherichia-coli-o157h7-and-staphylococcus-aureus-to-human-ht-29-cells-pmc): Historically, honey is known for its anti-bacterial and anti-fungal activities and its use for treatment of wound infections. Although this practice has been in place for millennia, little information exists regarding which manuka honey components ...
- [Honey therapies for dermatological disorders: more than just a sweet elixir - PubMed](https://umf.brandkitapp.com/asset-page/669828-honey-therapies-for-dermatological-disorders-more-than-just-a-sweet-elixir-pubmed) : Honey possesses antibacterial, anti-inflammatory, and healing properties that benefit wound healing and tissue regeneration. For centuries, honey has been utilized in traditional medicine as a binder or vehicle for creams and lotions and also for therapeutic purposes. The overuse of antibiotics and …
- [Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis - PubMed](https://umf.brandkitapp.com/asset-page/668683-effectiveness-of-honey-for-symptomatic-relief-in-upper-respiratory-tract-infections-a-systematic-review-and-meta-analysis-pubmed) : Study ID, CRD42017067582 on PROSPERO: International prospective register of systematic reviews (https://www.crd.york.ac.uk/prospero/).
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The Effect of Manuka Honey on dHL-60 Cytokine, Chemokine, and Matrix-Degrading Enzyme Release under Inflammatory Conditions - PMC
](https://umf.brandkitapp.com/asset-page/668682-the-effect-of-manuka-honey-on-dhl-60-cytokine-chemokine-and-matrix-degrading-enzyme-release-under-inflammatory-conditions-pmc): A large body of in vivo and in vitro evidence indicates that Manuka honey resolves inflammation and promotes healing when applied topically to a wound. In this study, the effect of two different concentrations (0.5% and 3% v/v) of Manuka honey on ...
- [Manuka Honey's Antifungal Power: Research & Uses | Manukora](https://umf.brandkitapp.com/asset-page/668681-manuka-honeys-antifungal-power-research-uses-manukora) : Explore the proven antifungal properties of Mānuka honey. Discover the latest research and applications that make it a potent natural remedy.
- [Honey has an antifungal effect against Candida species - PubMed](https://umf.brandkitapp.com/asset-page/668679-honey-has-an-antifungal-effect-against-candida-species-pubmed) : The incidence of Candida infections is escalating worldwide. The serious nature of these infections is compounded by increasing levels of drug resistance. We report that certain honeys have significant antifungal activity against clinical isolates of Candida species. Importantly, the minimum inhibit …
- [Utility of the Leptospermum scoparium Compound Lepteridine as a Chemical Marker for Manuka Honey Authenticity](https://umf.brandkitapp.com/asset-page/668678-utility-of-the-leptospermum-scoparium-compound-lepteridine-as-a-chemical-marker-for-manuka-honey-authenticity)
- [Honey Beats Antibiotics for Chronic Sinusitis](https://umf.brandkitapp.com/asset-page/668677-honey-beats-antibiotics-for-chronic-sinusitis) : Chronic rhinosinusitis associated with significant bodily pain that improves following surgery
- [The Medicine of the Manuka: An Investigation of the Usages and Methods for Utilization of Honey Derived From the Pollen of Leptospermum scoparium in Holistic Nursing Practice](https://umf.brandkitapp.com/asset-page/668675-the-medicine-of-the-manuka-an-investigation-of-the-usages-and-methods-for-utilization-of-honey-derived-from-the-pollen-of-leptospermum-scoparium-in-holistic-nursing-practice)
- [Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents - PubMed](https://umf.brandkitapp.com/asset-page/668673-effect-of-honey-dextromethorphan-and-no-treatment-on-nocturnal-cough-and-sleep-quality-for-coughing-children-and-their-parents-pubmed) : clinicaltrials.gov Identifier: NCT00127686.
- [Effect of honey on cardiometabolic risk factors: a systematic review and meta-analysis | Nutrition Reviews | Oxford Academic](https://umf.brandkitapp.com/asset-page/668671-effect-of-honey-on-cardiometabolic-risk-factors-a-systematic-review-and-meta-analysis-nutrition-reviews-oxford-academic) : AbstractContext. Excess calories from free sugars are implicated in the epidemics of obesity and type 2 diabetes. Honey is a free sugar but is generally re
- [Manuka honey, used in catheters, is proving effective in tackling infection](https://umf.brandkitapp.com/asset-page/668670-manuka-honey-used-in-catheters-is-proving-effective-in-tackling-infection) : Patients undergoing hospital treatment can face a challenge to recovery due to bacteria resistant to antibiotics. Read more.
- [Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains with different biofilm-forming abilities - PubMed](https://umf.brandkitapp.com/asset-page/668669-manuka-type-honeys-can-eradicate-biofilms-produced-by-staphylococcus-aureus-strains-with-different-biofilm-forming-abilities-pubmed) : Chronic wounds are a major global health problem. Their management is difficult and costly, and the development of antibiotic resistance by both planktonic and biofilm-associated bacteria necessitates the use of alternative wound treatments. Honey is now being revisited as an alternative treatment d …
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Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections: A Systematic Review - PMC
](https://umf.brandkitapp.com/asset-page/668668-clinical-significance-of-manuka-and-medical-grade-honey-for-antibiotic-resistant-infections-a-systematic-review-pmc): Antimicrobial resistance is an ever-increasing global issue that has the potential to overtake cancer as the leading cause of death worldwide by 2050. With the passing of the “golden age” of antibiotic discovery, identifying alternative treatments ...
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Honey: its medicinal property and antibacterial activity - PMC
](https://umf.brandkitapp.com/asset-page/668667-honey-its-medicinal-property-and-antibacterial-activity-pmc): Indeed, medicinal importance of honey has been documented in the world's oldest medical literatures, and since the ancient times, it has been known to possess antimicrobial property as well as wound-healing activity. The healing property of honey is ...
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Sensory, Microbiological and Physicochemical Characterisation of Functional Manuka Honey Yogurts Containing Probiotic Lactobacillus reuteri DPC16 - PMC
](https://umf.brandkitapp.com/asset-page/668666-sensory-microbiological-and-physicochemical-characterisation-of-functional-manuka-honey-yogurts-containing-probiotic-lactobacillus-reuteri-dpc16-pmc): Consumer acceptance of synbiotics, which are synergistic combinations of probiotics and their prebiotic substrates, continues to expand in the functional food category. This research aimed at evaluating the effect of antibacterial manuka honey on ...
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Antibacterial activity of Manuka honey and its components: An overview - PMC
](https://umf.brandkitapp.com/asset-page/668665-antibacterial-activity-of-manuka-honey-and-its-components-an-overview-pmc): The importance of honey for medicinal purposes is well documented in some of the world's oldest literature. Honey is well known and studied for its antimicrobial properties. The medicinal properties in honey originate from the floral source used by ...
- [Rifampicin-Manuka Honey Combinations Are Superior to Other Antibiotic-Manuka Honey Combinations in Eradicating Staphylococcus aureus Biofilms - PubMed](https://umf.brandkitapp.com/asset-page/668664-rifampicin-manuka-honey-combinations-are-superior-to-other-antibiotic-manuka-honey-combinations-in-eradicating-staphylococcus-aureus-biofilms-pubmed) : Chronic wound infections are a major burden to both society and the health care industry. Bacterial biofilms are the major cause of chronic wound infections and are notoriously recalcitrant to treatments with antibiotics, making them difficult to eradicate. Thus, new approaches are required to comba …
- [Frontiers | Antibiotic-specific differences in the response of Staphylococcus aureus to treatment with antimicrobials combined with manuka honey](https://umf.brandkitapp.com/asset-page/668663-frontiers-antibiotic-specific-differences-in-the-response-of-staphylococcus-aureus-to-treatment-with-antimicrobials-combined-with-manuka-honey) : Skin infections caused by antibiotic resistant Staphylococcus aureus are a significant health problem worldwide; often associated with high treatment cost an...
- [Antibiofilm Activity of Manuka Honey in Combination with Antibiotics - PubMed](https://umf.brandkitapp.com/asset-page/668662-antibiofilm-activity-of-manuka-honey-in-combination-with-antibiotics-pubmed) : We assessed the in vitro activity of Manuka honey against biofilm bacteria in combination with antibiotics and visualized the effect of Manuka honey on bacterial biofilms using scanning electron microscopy. The fractional biofilm eradication concentration (∑FBEC) index for vancomycin plus Manuka hon …
- [Synergy between oxacillin and manuka honey sensitizes methicillin-resistant Staphylococcus aureus to oxacillin | Journal of Antimicrobial Chemotherapy | Oxford Academic](https://umf.brandkitapp.com/asset-page/668661-synergy-between-oxacillin-and-manuka-honey-sensitizes-methicillin-resistant-staphylococcus-aureus-to-oxacillin-journal-of-antimicrobial-chemotherapy-oxford-academic) : AbstractObjectives. Honey is an ancient wound remedy that has recently been introduced into modern clinical practice in developed countries. Manuka honey i
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In vitro synergy between manuka honey and amikacin against Mycobacterium abscessus complex shows potential for nebulisation therapy
— Aston Research Explorer](https://umf.brandkitapp.com/asset-page/668660-in-vitro-synergy-between-manuka-honey-and-amikacin-against-mycobacterium-abscessus-complex-shows-potential-for-nebulisation-therapy-mdash-aston-research-explorer) : In vitro synergy between manuka honey and amikacin against Mycobacterium abscessus complex shows potential for nebulisation therapy
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Manuka Honey Modulates the Release Profile of a dHL-60 Neutrophil Model under Anti-Inflammatory Stimulation - PMC
](https://umf.brandkitapp.com/asset-page/668657-manuka-honey-modulates-the-release-profile-of-a-dhl-60-neutrophil-model-under-anti-inflammatory-stimulation-pmc): Manuka honey, a wound treatment used to eradicate bacteria, resolve inflammation, and promote wound healing, is a current focus in the tissue engineering community as a tissue template additive. However, Manuka honey’s effect on neutrophils during ...
- [Proteomic analysis of honey. Identification of unique peptide markers for authentication of NZ mānuka (Leptospermum scoparium) honey](https://umf.brandkitapp.com/asset-page/668653-proteomic-analysis-of-honey-identification-of-unique-peptide-markers-for-authentication-of-nz-manuka-leptospermum-scoparium-honey)
- [Antibacterial activity of varying UMF-graded Manuka honeys | PLOS ONE](https://umf.brandkitapp.com/asset-page/668651-antibacterial-activity-of-varying-umf-graded-manuka-honeys-plos-one) : Honey has been used as a traditional remedy for skin and soft tissue infections due to its ability to promote wound healing. Manuka honey is recognized for its unusually abundant content of the antibacterial compound, methylglyoxal (MGO). The Unique Manuka Factor (UMF) grading system reflects the MGO concentration in Manuka honey sold commercially. Our objective was to observe if UMF values correlated with the antibacterial activity of Manuka honey against a variety of pathogens purchased over the counter. The antibacterial effect of Manuka honey with UMF values of 5+, 10+, and 15+ from the same manufacturer was assessed by the broth microdilution method. Minimum inhibitory concentration (MIC) values were determined against 128 isolates from wound cultures representing gram-positive, gram-negative, drug-susceptible, and multi-drug resistant (MDR) organisms. Lower MICs were observed with UMF 5+ honey for staphylococci (n = 73, including 25 methicillin-resistant S. aureus) and Pseudomonas aeruginosa (n = 22, including 10 MDR) compared to UMF 10+ honey (p<0.05) and with UMF 10+ compared to UMF 15+ (p = 0.01). For Enterobacteriaceae (n = 33, including 14 MDR), MIC values were significantly lower for UMF 5+ or UMF 10+ compared to UMF 15+ honey (p<0.01). MIC50 for UMF 5+, UMF 10+, and UMF 15+ honey against staphylococci was 6%, 7%, and 15%, and for Enterobacteriaceae was 21%, 21%, and 27%, respectively. For Pseudomonas aeruginosa MIC50 was 21% and MIC90 was 21–27% for all UMFs. Manuka honey exhibited antimicrobial activity against a spectrum of organisms including those with multi-drug resistance, with more potent activity overall against gram-positive than gram-negative bacteria. Manuka honey with lower UMF values, in our limited sampling, paradoxically demonstrated increased antimicrobial activity among the limited samples tested, presumably due to changes in MGO content of honey over time. The UMF value by itself may not be a reliable indicator of antibacterial effect.
- [Identification of some antibacterial constituents of New Zealand manuka honey](https://umf.brandkitapp.com/asset-page/668649-identification-of-some-antibacterial-constituents-of-new-zealand-manuka-honey)
- [Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand - PubMed](https://umf.brandkitapp.com/asset-page/668648-identification-and-quantification-of-methylglyoxal-as-the-dominant-antibacterial-constituent-of-manuka-leptospermum-scoparium-honeys-from-new-zealand-pubmed) : The 1,2-dicarbonyl compounds 3-deoxyglucosulose (3-DG), glyoxal (GO), and methylglyoxal (MGO) were measured as the corresponding quinoxalines after derivatization with orthophenylendiamine using RP-HPLC and UV-detection in commercially available honey samples. Whereas for most of the samples values …
- [Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial - PubMed](https://umf.brandkitapp.com/asset-page/668647-effect-of-manuka-honey-on-eyelid-wound-healing-a-randomized-controlled-trial-pubmed) : Upper eyelid scars treated with or without Manuka honey heal well, without significant difference when assessed by validated scar grading scales; however, honey may provide subjective benefits early, postoperatively.
- [Manuka honey inhibits the development of Streptococcus pyogenes biofilms and causes reduced expression of two fibronectin binding proteins - PubMed](https://umf.brandkitapp.com/asset-page/668646-manuka-honey-inhibits-the-development-of-streptococcus-pyogenes-biofilms-and-causes-reduced-expression-of-two-fibronectin-binding-proteins-pubmed) : Streptococcus pyogenes (group A Streptococcus; GAS) is always of clinical significance in wounds where it can initiate infection, destroy skin grafts and persist as a biofilm. Manuka honey has broad spectrum antimicrobial activity and its use in the clinical setting is beginning to gain acceptance w …
- [Manuka honey inhibits adhesion and invasion of medically important wound bacteria in vitro - PubMed](https://umf.brandkitapp.com/asset-page/668645-manuka-honey-inhibits-adhesion-and-invasion-of-medically-important-wound-bacteria-in-vitro-pubmed) : Manuka honey can directly affect bacterial cells embedded in a biofilm and exhibits antiadhesive properties against three common wound pathogens.
- [Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial - PubMed](https://umf.brandkitapp.com/asset-page/668644-manuka-honey-sinus-irrigation-for-the-treatment-of-chronic-rhinosinusitis-a-randomized-controlled-trial-pubmed) : In patients with active CRS and prior sinus surgery, both MH and SAL improved outcomes, but there was no statistically significant difference between these groups. However, in the subset that did not receive oral antibiotics/steroids, culture negativity was statistically better on MH, suggesting tha …
- [Antibacterial Honey: in-vitro Activity Against Clinical Isolates of MRSA, VRE, and Other Multiresistant Gram-negative Organisms](https://umf.brandkitapp.com/asset-page/668643-antibacterial-honey-in-vitro-activity-against-clinical-isolates-of-mrsa-vre-and-other-multiresistant-gram-negative-organisms)
- [A review of research into second intention equine wound healing using manuka honey: Current … - ](https://umf.brandkitapp.com/asset-page/668642-a-review-of-research-into-second-intention-equine-wound-healing-using-manuka-honey-current)
- [The unusual antibacterial activity of medical-grade Leptospermum honey: antibacterial spectrum, resistance and transcriptome analysis - PubMed](https://umf.brandkitapp.com/asset-page/668641-the-unusual-antibacterial-activity-of-medical-grade-leptospermum-honey-antibacterial-spectrum-resistance-and-transcriptome-analysis-pubmed) : There is an urgent need for new, effective agents in topical wound care, and selected honeys show potential in this regard. Using a medical-grade honey, eight species of problematic wound pathogens, including those with high levels of innate or acquired antibiotic resistance, were killed by 4.0-14.8 …
- [Evidence against dietary advanced glycation endproducts being a risk to human health - PubMed](https://umf.brandkitapp.com/asset-page/668640-evidence-against-dietary-advanced-glycation-endproducts-being-a-risk-to-human-health-pubmed) : In vivo, advanced glycation endproducts (AGEs) are linked to various diseases, particularly those associated with diabetes. AGEs are also formed when many foods are thermally processed. The extent to which dietary AGEs are absorbed by the gastrointestinal (GI) tract and their possible role in the on …
- [A survey of the antibacterial activity of some New Zealand honeys - PubMed](https://umf.brandkitapp.com/asset-page/668639-a-survey-of-the-antibacterial-activity-of-some-new-zealand-honeys-pubmed) : To assess the variation in antibacterial activity of honey a survey was carried out on 345 samples of unpasteurized honey obtained from commercial apiarists throughout New Zealand. Most of the honeys were considered to be monofloral, from 26 different floral sources. The honeys were tested against S …
- [The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 2: Induction of oxidative stress, alteration of mitochondrial respiration and glycolysis, and suppression of metastatic ability - PubMed](https://umf.brandkitapp.com/asset-page/668638-the-inhibitory-effect-of-manuka-honey-on-human-colon-cancer-hct-116-and-lovo-cell-growth-part-2-induction-of-oxidative-stress-alteration-of-mitochondrial-respiration-and-glycolysis-and-suppression-of-metastatic-ability-pubmed) : Despite its high content of phenolic compounds, the chemopreventive activity of Manuka honey (MH) is still elusive. The aim of the present work was to evaluate the effects of MH on oxidative stress, antioxidant enzymes, cellular metabolism and the metastatic ability in HCT-116 and LoVo cells, paying …
- [The origin of methylglyoxal in New Zealand manuka (Leptospermum scoparium) honey](https://umf.brandkitapp.com/asset-page/668636-the-origin-of-methylglyoxal-in-new-zealand-manuka-leptospermum-scoparium-honey)
- [Effect of Manuka honey gel on the transforming growth factor β1 and β3 concentrations, bacterial counts and histomorphology of contaminated full-thickness skin wounds in equine distal limbs](https://umf.brandkitapp.com/asset-page/657912-effect-of-manuka-honey-gel-on-the-transforming-growth-factor-1-and-3-concentrations-bacterial-counts-and-histomorphology-of-contaminated-full-thickness-skin-wounds-in-equine-distal-limbs)
- [A split-body, randomized, blinded study to evaluate the efficacy of a topical spray composed of essential oils and essential fatty acids from plant extracts with antimicrobial properties](https://umf.brandkitapp.com/asset-page/657911-a-split-body-randomized-blinded-study-to-evaluate-the-efficacy-of-a-topical-spray-composed-of-essential-oils-and-essential-fatty-acids-from-plant-extracts-with-antimicrobial-properties)
- [Comparison of the effects of topical application of UMF20 and UMF5 manuka honey with a generic multifloral honey on wound healing variables in an uncontaminated surgical equine distal limb wound model](https://umf.brandkitapp.com/asset-page/657910-comparison-of-the-effects-of-topical-application-of-umf20-and-umf5-manuka-honey-with-a-generic-multifloral-honey-on-wound-healing-variables-in-an-uncontaminated-surgical-equine-distal-limb-wound-model)
- [Effects of topical treatment of cannabidiol extract in a unique manuka factor 5 manuka honey carrier on second intention wound healing on equine distal limb wounds: a preliminary study](https://umf.brandkitapp.com/asset-page/657909-effects-of-topical-treatment-of-cannabidiol-extract-in-a-unique-manuka-factor-5-manuka-honey-carrier-on-second-intention-wound-healing-on-equine-distal-limb-wounds-a-preliminary-study)
- [Hyaluronic acid, Manuka honey and Acemannan gel: Wound-specific applications for skin lesions - ScienceDirect](https://umf.brandkitapp.com/asset-page/657908-hyaluronic-acid-manuka-honey-and-acemannan-gel-wound-specific-applications-for-skin-lesions-sciencedirect) : Hyaluronic acid, Manuka honey and Acemannan gel: Wound-specific applications for skin lesions
- [Medical honey for canine nasal intertrigo: A randomized, blinded, placebo-controlled, adaptive clinical trial to support antimicrobial stewardship in veterinary dermatology | PLOS ONE](https://umf.brandkitapp.com/asset-page/657907-medical-honey-for-canine-nasal-intertrigo-a-randomized-blinded-placebo-controlled-adaptive-clinical-trial-to-support-antimicrobial-stewardship-in-veterinary-dermatology-plos-one) : Intertrigo is a skin fold dermatitis often requiring recurrent treatment with topical antiseptics or antibiotics, which can select antimicrobial resistance. To minimize this risk, we tested the effectiveness of medical-grade Manuka honey at treating intertrigo as compared to a placebo hydrogel. We additionally characterized the culturable microbial flora of intertrigo and recorded any adverse effect with either treatment. During this randomized, placebo-controlled, double-blinded, adaptive group-sequential trial, the owners washed the affected sites on their dog with water, dried and applied a thin film of either the honey or the placebo product once daily for 21 days. Cytological and lesional composite scores, owner-assessed pruritus, and microbial cultures were assessed prior to treatment and on Day-22. The fixed effects of time, treatment, and animal-related variables on the pruritus and on each composite score, accounting for random dog effect, were estimated separately with generalized linear mixed models for repeated count outcomes (α = 0.05). The null hypothesis of equal treatment effects was rejected at the first interim analysis. The placebo (n = 16 dogs) outperformed the medical honey (n = 13 dogs) at improving both the cytological score (Treatment×Time = -0.35±0.17; P = 0.04) and clinical score (Treatment×Time = -0.28±0.13; P = 0.04). A microbial burden score higher than 4 increased the severity of the cytological score (dichotomous score: 0.29±0.11; P = 0.01), which in turn increased the severity of the clinical score and pruritus score. For every unit increase in cytological score, the linear predictor of clinical score increased by 0.042±0.019 (P = 0.03), and the one of pruritus score increased by 0.12±0.05 (P = 0.01). However, medical honey outperformed the placebo at alleviating the dog’s owner-assessed pruritus after statistically controlling for masking effects (Time = -0.94±0.24; P = 0.002; and Treatment×Time = 0.80±0.36; P = 0.04). Unilateral tests of the least-square mean estimates revealed that honey only significantly improved the pruritus (Hommel-adjusted P = 0.003), while the placebo only improved the cytological and clinical scores (Hommel-adjusted P = 0.01 and 0.002, respectively). Taken together, these results question the value of Manuka honey at treating nasal intertrigo in dogs.
- [A randomised trial of honey barrier cream versus zinc oxide ointment - PubMed](https://umf.brandkitapp.com/asset-page/657864-a-randomised-trial-of-honey-barrier-cream-versus-zinc-oxide-ointment-pubmed) : In this single-blind multicentre, intervention study, 31 patients with symmetrical intertrigo in large skin folds were included to study the clinical effect of two topical treatments, i.e. standard therapy with zinc oxide ointment versus honey barrier cream. Patients were treated twice daily for 21 …
- [Honey and Medihoney® Barrier Cream: their role in protecting and repairing skin](https://umf.brandkitapp.com/asset-page/657748-honey-and-medihoney-barrier-cream-their-role-in-protecting-and-repairing-skin)
- [Objective and subjective scar aesthetics with topical Manuka honey post-thyroidectomy: A randomized control study - ScienceDirect](https://umf.brandkitapp.com/asset-page/657747-objective-and-subjective-scar-aesthetics-with-topical-manuka-honey-post-thyroidectomy-a-randomized-control-study-sciencedirect) : Objective and subjective scar aesthetics with topical Manuka honey post-thyroidectomy: A randomized control study
- [A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer - PMC](https://umf.brandkitapp.com/asset-page/657746-a-pilot-randomized-controlled-study-of-nanocrystalline-silver-manuka-honey-and-conventional-dressing-in-healing-diabetic-foot-ulcer-pmc) : A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer
- [Manuka Honey: A Case Study of Severe Atopic Eczematous Dermatitis Reaction to Henna Tattoo - PubMed](https://umf.brandkitapp.com/asset-page/657745-manuka-honey-a-case-study-of-severe-atopic-eczematous-dermatitis-reaction-to-henna-tattoo-pubmed) : Many mainstream medications were derived from plants and originally utilized in patient management well prior to the extensive research and testing processes of current pharmaceutical standards. The evolution of therapeutic management within the pharmaceutical and skin care industry often uses synth …
- [Moisture-associated skin damage: use of a skin protectant containing manuka honey](https://umf.brandkitapp.com/asset-page/657743-moisture-associated-skin-damage-use-of-a-skin-protectant-containing-manuka-honey)
- [Resolution of folliculitis decalvans with medical honey](https://umf.brandkitapp.com/asset-page/657742-resolution-of-folliculitis-decalvans-with-medical-honey) : Author(s): Yeh, Jennifer E; Hartman, Rebecca I; Xu, Jia; Hoang, Mai; Yasuda, Mariko R | Abstract: Folliculitis decalvans is a rare scarring alopecia that presents with indurated, tender pustules and papules on the vertex and occipital scalp. Although systemic antibiotics with activity against Staphylococcus species provide some symptomatic improvement, folliculitis decalvans remains a significant management challenge and often exhibits a relapsing-and-remitting course. In this report, we posit the potential utility of medical grade honey as a safe and cost-effective adjuvant therapy in the treatment of folliculitis decalvans. We describe a patient with painful, boggy scalp pustules who achieved clearance of his scalp lesions with the addition of Manuka honey. To our knowledge, this report is the first to demonstrate the clinical use of honey in the management of folliculitis decalvans and may lend support to the role of Staphylococcus in the pathogenesis of this disease.
- [Comparative Evaluation of Wound Healing Potential of Manuka and Acacia Honey in Diabetic and Nondiabetic Rats - PMC](https://umf.brandkitapp.com/asset-page/657740-comparative-evaluation-of-wound-healing-potential-of-manuka-and-acacia-honey-in-diabetic-and-nondiabetic-rats-pmc) : Comparative Evaluation of Wound Healing Potential of Manuka and Acacia Honey in Diabetic and Nondiabetic Rats
- [Pediatric Critical Care Medicine](https://umf.brandkitapp.com/asset-page/657739-pediatric-critical-care-medicine) : Use of Honey Versus Standard Care for Hospital-Acquired... : Pediatric Critical Care Medicine
- [Journal of Wound Ostomy & Continence Nursing](https://umf.brandkitapp.com/asset-page/657737-journal-of-wound-ostomy-continence-nursing) : Successful Treatment of a Venous Leg Ulcer With Manuka... : Journal of Wound Ostomy & Continence Nursing
- [Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial](https://umf.brandkitapp.com/asset-page/657635-manuka-honey-sinus-irrigation-for-the-treatment-of-chronic-rhinosinusitis-a-randomized-controlled-trial)
- [Effectiveness of three mouthwashes & Manuka honey, Raw honey, and Chlorhexidine on plaque and gingival scores of 12-15-year-old school children: A randomized controlled field trial - PMC](https://umf.brandkitapp.com/asset-page/657634-effectiveness-of-three-mouthwashes-manuka-honey-raw-honey-and-chlorhexidine-on-plaque-and-gingival-scores-of-12-15-year-old-school-children-a-randomized-controlled-field-trial-pmc) : Effectiveness of three mouthwashes – Manuka honey, Raw honey, and Chlorhexidine on plaque and gingival scores of 12–15-year-old school children: A randomized controlled field trial
- [Randomized controlled trial of honey versus mupirocin to decolonize patients with nasal colonization of meticillin-resistant Staphylococcus aureus](https://umf.brandkitapp.com/asset-page/657633-randomized-controlled-trial-of-honey-versus-mupirocin-to-decolonize-patients-with-nasal-colonization-of-meticillin-resistant-staphylococcus-aureus)
- [The association of Leptospermum honey with cytokine expression in the sinonasal epithelium of chronic rhinosinusitis patients - ScienceDirect](https://umf.brandkitapp.com/asset-page/657632-the-association-of-leptospermum-honey-with-cytokine-expression-in-the-sinonasal-epithelium-of-chronic-rhinosinusitis-patients-sciencedirect) : The association of Leptospermum honey with cytokine expression in the sinonasal epithelium of chronic rhinosinusitis patients
- [Manuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single-blinded, placebo-controlled trial](https://umf.brandkitapp.com/asset-page/657631-manuka-honey-sinus-irrigations-in-recalcitrant-chronic-rhinosinusitis-phase-1-randomized-single-blinded-placebo-controlled-trial)
- [Effect of Intrasocket Application of Manuka Honey on Postsurgical Pain of Impacted Mandibular Third Molars Surgery: Split-Mouth Randomized Controlled Trial - PMC](https://umf.brandkitapp.com/asset-page/657630-effect-of-intrasocket-application-of-manuka-honey-on-postsurgical-pain-of-impacted-mandibular-third-molars-surgery-split-mouth-randomized-controlled-trial-pmc) : Effect of Intrasocket Application of Manuka Honey on Postsurgical Pain of Impacted Mandibular Third Molars Surgery: Split-Mouth Randomized Controlled Trial
- [The influence of intra-alveolar application of honey versus Chlorhexidine rinse on the incidence of Alveolar Osteitis following molar teeth extraction. A randomized clinical parallel trial - PMC](https://umf.brandkitapp.com/asset-page/657621-the-influence-of-intra-alveolar-application-of-honey-versus-chlorhexidine-rinse-on-the-incidence-of-alveolar-osteitis-following-molar-teeth-extraction-a-randomized-clinical-parallel-trial-pmc) : The influence of intra-alveolar application of honey versus Chlorhexidine rinse on the incidence of Alveolar Osteitis following molar teeth extraction. A randomized clinical parallel trial
- [Manuka honey versus saline sinus irrigation in the treatment of cystic fibrosis-associated chronic rhinosinusitis: A randomised pilot trial](https://umf.brandkitapp.com/asset-page/657620-manuka-honey-versus-saline-sinus-irrigation-in-the-treatment-of-cystic-fibrosis-associated-chronic-rhinosinusitis-a-randomised-pilot-trial): Manuka honey irrigations were well tolerated, and retention rates were high. Preliminary data showed that manuka honey achieved a clinically important difference in quality-of-life score and a significantly better endoscopic outcome. Microbiological control was difficult to achieve. A future definitive trial would require multi-institutional recruitment.
- [Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study - PMC](https://umf.brandkitapp.com/asset-page/657619-morphometric-analysis-of-the-effects-of-manuka-honey-on-vasospastic-femoral-arteries-in-rats-an-experimental-study-pmc) : Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study
- [Dynamics of the Cellular Metabolism of Leptosperin Found in Manuka Honey](https://umf.brandkitapp.com/asset-page/657618-dynamics-of-the-cellular-metabolism-of-leptosperin-found-in-manuka-honey): Leptosperin (methyl syringate β-d-gentiobioside) is abundantly found in manuka honey, which is widely used because of its antibacterial and possible anti-inflammatory activities. The aim of this study was to examine the molecular mechanism underlying the metabolism of leptosperin. Five phytochemicals (leptosperin, methyl syringate (MSYR), glucuronate conjugate of MSYR (MSYR-GA), sulfonate conjugate of MSYR (MSYR-S), and syringic acid (SYR)) were separately incubated with HepG2 and Caco-2 cells. After incubation, we found that the concentration of MSYR decreased, whereas the concentrations of SYR, MSYR-GA, and MSYR-S increased. By profiling with inhibitors and carboxylesterases (CES1, 2), we found that the conversion from MSYR to SYR was mediated by CES1. Lipopolysaccharide-stimulated RAW264.7 cells restored MSYR-GA to MSYR possibly by the secreted β-glucuronidase. All of the mice administered with leptosperin, MSYR, or manuka honey showed higher MSYR (13.84 ± 11.51, 14.29 ± 9.19, or 6.66 ± 2.30 nM) and SYR (1.85 ± 0.66, 6.01 ± 1.20, or 8.16 ± 3.10 nM) levels in the plasma compared with that of the vehicle controls (3.33 ± 1.45 (MSYR) and 1.85 ± 0.66 (SYR) nM). The findings of our study indicate that the unique metabolic pathways of these compounds may account for possible functionalities of manuka honey.
- [In vivo absorption and metabolism of leptosperin and methyl syringate, abundantly present in manuka honey](https://umf.brandkitapp.com/asset-page/657617-in-vivo-absorption-and-metabolism-of-leptosperin-and-methyl-syringate-abundantly-present-in-manuka-honey)
- [Consumption of antimicrobial manuka honey does not significantly perturb the microbiota in the hind gut of mice - PMC](https://umf.brandkitapp.com/asset-page/657616-consumption-of-antimicrobial-manuka-honey-does-not-significantly-perturb-the-microbiota-in-the-hind-gut-of-mice-pmc) : Consumption of antimicrobial manuka honey does not significantly perturb the microbiota in the hind gut of mice
- [Molecular Mechanisms of Natural Honey Against H. pylori Infection Via Suppression of NF-κB and AP-1 Activation in Gastric Epithelial Cells - ScienceDirect](https://umf.brandkitapp.com/asset-page/657615-molecular-mechanisms-of-natural-honey-against-h-pylori-infection-via-suppression-of-nf-b-and-ap-1-activation-in-gastric-epithelial-cells-sciencedirect) : Molecular Mechanisms of Natural Honey Against H. pylori Infection Via Suppression of NF-κB and AP-1 Activation in Gastric Epithelial Cells
- [Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats - PMC](https://umf.brandkitapp.com/asset-page/657605-manuka-honey-exerts-antioxidant-and-anti-inflammatory-activities-that-promote-healing-of-acetic-acid-induced-gastric-ulcer-in-rats-pmc) : Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats
- [Treatment of contact lens related dry eye with antibacterial honey](https://umf.brandkitapp.com/asset-page/657604-treatment-of-contact-lens-related-dry-eye-with-antibacterial-honey): Dry eye symptoms improved significantly after Optimel treatment. Patients with more severe symptoms at baseline showed a greater improvement in symptoms. No significant differences were observed in the objective signs of dry eye; presumably because of the short treatment duration. Seventy-five% of contact lens wearers reported good adherence to Optimel treatment and 95% reported no issues using this product.
- [Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial](https://umf.brandkitapp.com/asset-page/657603-effect-of-manuka-honey-on-eyelid-wound-healing-a-randomized-controlled-trial): Upper eyelid scars treated with or without Manuka honey heal well, without significant difference when assessed by validated scar grading scales; however, honey may provide subjective benefits early, postoperatively.
- [Randomised masked trial of the clinical safety and tolerability of MGO Manuka Honey eye cream for the management of blepharitis - PMC](https://umf.brandkitapp.com/asset-page/657602-randomised-masked-trial-of-the-clinical-safety-and-tolerability-of-mgo-manuka-honey-eye-cream-for-the-management-of-blepharitis-pmc) : Randomised masked trial of the clinical safety and tolerability of MGO Manuka Honey eye cream for the management of blepharitis
- [Preclinical development of MGO Manuka Honey microemulsion for blepharitis management | BMJ Open Ophthalmology](https://umf.brandkitapp.com/asset-page/657601-preclinical-development-of-mgo-manuka-honey-microemulsion-for-blepharitis-management-bmj-open-ophthalmology) : Objective To evaluate the in vitro antimicrobial effects of cyclodextrin-complexed and uncomplexed Manuka honey on bacteria commonly associated with blepharitis, and in vivo rabbit eye tolerability of a cyclodextrin-complexed methylglyoxal (MGO) Manuka Honey microemulsion (MHME).Methods and analysis In vitro phase: Bacterial growth inhibition was assessed by area under the growth curve (AUC) for Staphylococcus aureus, and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for S. aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa with cyclodextrin-complexed and uncomplexed Manuka honey were determined. In vivo phase: Six rabbits were administered 20 µL of MHME (at 1:10 dilution) to the right eye (treated) and 20 µL of saline to the left eye (control) daily, for 5 days. Tear evaporation, production, osmolarity, lipid layer, conjunctival hyperaemia and fluorescein staining were assessed daily, before and 15 min after instillation.Results In vitro phase: The relative AUC for cyclodextrin-complexed Manuka honey was lower than that of uncomplexed honey at both 250 and 550 mg/kg of MGO (both p <0.05). Cyclodextrin-complexed honey had lower MIC and MBC than uncomplexed honey for both S. aureus and S. epidermidis, but not P. aeruginosa. In vivo phase: No significant changes were observed in the parameters assessed in either treated or control eyes (all p >0.05).Conclusion Overall, antimicrobial potency of cyclodextrin-complexed Manuka honey was greater than uncomplexed honey. No significant immediate or cumulative adverse effects were observed with MHME application on rabbit eyes, supporting future conduct of clinical safety and tolerability trials in human subjects.
- [Randomised controlled trial of topical antibacterial Manuka (Leptospermum species) honey for evaporative dry eye due to meibomian gland dysfunction](https://umf.brandkitapp.com/asset-page/657600-randomised-controlled-trial-of-topical-antibacterial-manuka-leptospermum-species-honey-for-evaporative-dry-eye-due-to-meibomian-gland-dysfunction)
- [Randomized masked trial of the clinical efficacy of MGO Manuka Honey microemulsion eye cream for the treatment of blepharitis - ScienceDirect](https://umf.brandkitapp.com/asset-page/657599-randomized-masked-trial-of-the-clinical-efficacy-of-mgo-manuka-honey-microemulsion-eye-cream-for-the-treatment-of-blepharitis-sciencedirect) : Randomized masked trial of the clinical efficacy of MGO Manuka Honey microemulsion eye cream for the treatment of blepharitis
- [Randomised assessor-masked trial evaluating topical manuka honey (Optimel) in treatment of meibomian gland dysfunction | British Journal of Ophthalmology](https://umf.brandkitapp.com/asset-page/657598-randomised-assessor-masked-trial-evaluating-topical-manuka-honey-optimel-in-treatment-of-meibomian-gland-dysfunction-british-journal-of-ophthalmology) : Randomised assessor-masked trial evaluating topical manuka honey (Optimel) in treatment of meibomian gland dysfunction
- [Particulate systems based on pectin/chitosan association for the delivery of manuka honey components and platelet lysate in chronic skin ulcers - ScienceDirect](https://umf.brandkitapp.com/asset-page/657597-particulate-systems-based-on-pectinchitosan-association-for-the-delivery-of-manuka-honey-components-and-platelet-lysate-in-chronic-skin-ulcers-sciencedirect) : Particulate systems based on pectin/chitosan association for the delivery of manuka honey components and platelet lysate in chronic skin ulcers
- [Application of DoE approach in the development of mini-capsules, based on biopolymers and manuka honey polar fraction, as powder formulation for the treatment of skin ulcers - ScienceDirect](https://umf.brandkitapp.com/asset-page/657596-application-of-doe-approach-in-the-development-of-mini-capsules-based-on-biopolymers-and-manuka-honey-polar-fraction-as-powder-formulation-for-the-treatment-of-skin-ulcers-sciencedirect) : Application of DoE approach in the development of mini-capsules, based on biopolymers and manuka honey polar fraction, as powder formulation for the treatment of skin ulcers
- [Scar free healing mediated by the release of aloe vera and manuka honey from dextran bionanocomposite wound dressings - ScienceDirect](https://umf.brandkitapp.com/asset-page/657590-scar-free-healing-mediated-by-the-release-of-aloe-vera-and-manuka-honey-from-dextran-bionanocomposite-wound-dressings-sciencedirect) : Scar free healing mediated by the release of aloe vera and manuka honey from dextran bionanocomposite wound dressings
- [Advances in cartilage repair: The influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels - ScienceDirect](https://umf.brandkitapp.com/asset-page/657589-advances-in-cartilage-repair-the-influence-of-inorganic-clays-to-improve-mechanical-and-healing-properties-of-antibacterial-gellan-gum-manuka-honey-hydrogels-sciencedirect) : Advances in cartilage repair: The influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels
- [Oral Administration of Tualang and Manuka Honeys Modulates Breast Cancer Progression in Sprague-Dawley Rats Model - PMC](https://umf.brandkitapp.com/asset-page/657588-oral-administration-of-tualang-and-manuka-honeys-modulates-breast-cancer-progression-in-sprague-dawley-rats-model-pmc) : Oral Administration of Tualang and Manuka Honeys Modulates Breast Cancer Progression in Sprague-Dawley Rats Model
- [Honey and its nutritional and anti-inflammatory value | BMC Complementary Medicine and Therapies | Full Text](https://umf.brandkitapp.com/asset-page/657171-honey-and-its-nutritional-and-anti-inflammatory-value-bmc-complementary-medicine-and-therapies-full-text) : Inflammation is the main key role in developing chronic diseases including cancer, cardiovascular diseases, diabetes, arthritis, and neurodegenerative diseases which possess a huge challenge for treatment. With massively compelling evidence of the role played by nutritional modulation in preventing inflammation-related diseases, there is a growing interest into the search for natural functional foods with therapeutic and preventive actions. Honey, a nutritional healthy product, is produced mainly by two types of bees: honeybee and stingless bee. Since both types of honey possess distinctive phenolic and flavonoid compounds, there is recently an intensive interest in their biological and clinical actions against inflammation-mediated chronic diseases. This review shed the light specifically on the bioavailability and bioaccessibility of honey polyphenols and highlight their roles in targeting inflammatory pathways in gastrointestinal tract disorders, edema, cancer, metabolic and cardiovascular diseases and gut microbiota.
- [Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats - PubMed](https://umf.brandkitapp.com/asset-page/657170-antioxidant-anti-inflammatory-and-antiulcer-potential-of-manuka-honey-against-gastric-ulcer-in-rats-pubmed) : Gastric ulcers are among the most common diseases affecting humans. This study aimed at investigating the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats. The mechanism by which honey exerts its antiulcer potential was elucidated. Four groups of rats were used …
- [Honey for wound care in the 21st century](https://umf.brandkitapp.com/asset-page/657169-honey-for-wound-care-in-the-21st-century): This review is written in memory of Professor Peter Molan, who published a paper in the Journal of Wound Care in 1999 describing the therapeutic properties of honey in relation to wound care. It provides an update to show how our understanding of the mode of action of honey has changed within the past 17 years.
- [Methylglyoxal, the Major Antibacterial Factor in Manuka Honey: An Alternative to Preserve Natural Cosmetics?](https://umf.brandkitapp.com/asset-page/657168-methylglyoxal-the-major-antibacterial-factor-in-manuka-honey-an-alternative-to-preserve-natural-cosmetics) : Microbial safety is an essential prerequisite of cosmetics, and preservatives are required to prevent product spoilage and damage to consumers’ health. Consumer concern about the safety of some cosmetic ingredients and the increasing demand for more natural beauty products has driven cosmetic industries and formulators to find natural alternatives to replace synthetic preservatives currently used. In this study, methylglyoxal (MGO, the main factor responsible for the antimicrobial activity of manuka honey) was tested for antimicrobial activity against a panel of selected bacteria and mycetes by using conventional microbiological techniques (determination of M.I.C., time-kill assay), and its potential preservative in an O/W emulsion was investigated (challenge test). MGO showed a remarkable and fast antibacterial activity (M.I.C. values 0.150–0.310 mg/mL), while the inhibitory activity against fungi was less marked (M.I.C. values 1.25–10 mg/mL); chitosan has proven to be a synergist of antimicrobial effectiveness of MGO. Results of the challenge test showed that the addition of MGO to a cream formulation was efficient against microbial contamination. On the basis of our results, MGO appears to be a good candidate as a cosmetic preservative of natural origin; further studies are needed to confirm its applicability and its safety.
- [Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models - PubMed](https://umf.brandkitapp.com/asset-page/654091-manuka-honey-inhibits-human-breast-cancer-progression-in-preclinical-models-pubmed) : Manuka honey (MH) exhibits potential antitumor activity in preclinical models of a number of human cancers. Treatment in vitro with MH at concentrations ranging from 0.3 to 5.0% (w/v) led to significant dose-dependent inhibition of proliferation of human breast cancer MCF-7 cells, but …
- [Anti-influenza viral effects of honey in vitro: potent high activity of manuka honey - PubMed](https://umf.brandkitapp.com/asset-page/654090-anti-influenza-viral-effects-of-honey-in-vitro-potent-high-activity-of-manuka-honey-pubmed) : Our results showed that honey, in general, and particularly manuka honey, has potent inhibitory activity against the influenza virus, demonstrating a potential medicinal value.
- [Studies on bioactivities of Manuka and regional varieties of honey for their potential use as natural antibiotic agents for infection control related to wound healing and in pharmaceutical formulations](https://umf.brandkitapp.com/asset-page/654089-studies-on-bioactivities-of-manuka-and-regional-varieties-of-honey-for-their-potential-use-as-natural-antibiotic-agents-for-infection-control-related-to-wound-healing-and-in-pharmaceutical-formulations) : Presently, most of the reported infections are of a bacterial origin; however, this leads to a limit within the literature and research around infections caused by fungal pathogens, which are now developing resistance to antibiotic medicines. Of the natural antimicrobial agents, honey has been observed with demonstrable and highly exploitable antimicrobial and infection control related to wound healing properties; therefore, it has been incorporated into many standard pharmaceutical formulations. Generally, these products utilize a pure sample of honey as a bioactive ingredient in a product which has been purposely designed for the convenience of application. This article aims to review information available from published reports on various bioactivities of a variety of medical-grade honey products, including manuka and other conventional non-manuka types sourced from different floral types and geographical regions. Additionally, this review highlights the antibiotic activities of various types of honey products tested against pathogenic strains of bacteria, yeast and fungi, and their applications in the formulation of healthcare products.
- [In vitro synergy between manuka honey and amikacin against Mycobacterium abscessus complex shows potential for nebulisation therapy | Microbiology Society](https://umf.brandkitapp.com/asset-page/651459-in-vitro-synergy-between-manuka-honey-and-amikacin-against-mycobacterium-abscessus-complex-shows-potential-for-nebulisation-therapy-microbiology-society) : Mycobacterium abscessusis an opportunistic human pathogen of increasing concern, due to its ability to cause aggressive pulmonary infections (especially in cystic fibrosis patients), as well as skin and soft tissue infections. M. abscessus is intrinsically drug resistant and treatment regimens are lengthy, consisting of multiple antibiotics with severe side effects and poor patient success rates. New and novel strategies are urgently required to combat these infections. One such strategy thus far overlooked for mycobacteria is manuka honey. For millennia manuka honey has been shown to have wide ranging medicinal properties, which have more recently been identified for its broad spectrum of antimicrobial activity. Here we demonstrate that manuka honey can be used to inhibit M. abscessus and a variety of drug resistant clinical isolates in vitro. We also demonstrate using a microbroth dilution checkerboard assay that manuka honey works synergistically with amikacin, which is one of the current front line antibiotics used for treatment of M. abscessus infections. This was further validated using an in vitro inhalation model, where we showed that with the addition of manuka honey, the amikacin dosage can be lowered whilst increasing its efficacy. These findings demonstrate the utility of manuka honey for incorporation into nebulised antibiotic treatment for respiratory infections, in particular M. abscessus . These results pave the way for a change of strategy for M. abscessus management, offering new therapeutic options for this deadly infection.
- [Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections: A Systematic Review - PubMed](https://umf.brandkitapp.com/asset-page/651458-clinical-significance-of-manuka-and-medical-grade-honey-for-antibiotic-resistant-infections-a-systematic-review-pubmed) : Antimicrobial resistance is an ever-increasing global issue that has the potential to overtake cancer as the leading cause of death worldwide by 2050. With the passing of the "golden age" of antibiotic discovery, identifying alternative treatments to commonly used antimicrobials is more important th …
- [A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey | Archives of Microbiology](https://umf.brandkitapp.com/asset-page/651457-a-demonstration-of-the-susceptibility-of-clinical-isolates-obtained-from-cystic-fibrosis-patients-to-manuka-honey-archives-of-microbiology) : Pseudomonas and Burkholderia pose a significant health threat to people with chronic respiratory conditions; the resistance inherent in these bacteria indi
- [In vitro Study of Anti-Helicobacter pylori Activity of Honey: A Systematic Review](https://umf.brandkitapp.com/asset-page/651456-in-vitro-study-of-anti-helicobacter-pylori-activity-of-honey-a-systematic-review)
- [Antibacterial effect of Manuka honey on Clostridium difficile - PubMed](https://umf.brandkitapp.com/asset-page/651455-antibacterial-effect-of-manuka-honey-on-clostridium-difficile-pubmed) : C. difficile is appreciably susceptible to Manuka honey and this may offer an effective way of treating infections caused by the organism.
- [Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment - PubMed](https://umf.brandkitapp.com/asset-page/651454-effect-of-honey-in-preventing-gingivitis-and-dental-caries-in-patients-undergoing-orthodontic-treatment-pubmed) : Honey can be used as an alternative to traditional remedies for the prevention of dental caries and gingivitis following orthodontic treatment.
- [Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis | BMJ Evidence-Based Medicine](https://umf.brandkitapp.com/asset-page/651453-effectiveness-of-honey-for-symptomatic-relief-in-upper-respiratory-tract-infections-a-systematic-review-and-meta-analysis-bmj-evidence-based-medicine) : Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis
- [Foods | Free Full-Text | Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective](https://umf.brandkitapp.com/asset-page/651452-foods-free-full-text-antibacterial-and-antibiofilm-effect-of-honey-in-the-prevention-of-dental-caries-a-recent-perspective) : The successful application of honey in wound care management has been achieved due to honey’s potent antibacterial effects, characterised by its multifactorial action. Impressive clinical efficacy has ignited its further use in diverse clinical disciplines, including stomatology. Indeed, there is increasing usage of honey in dental medicine as a preventive or therapeutic remedy for some periodontal diseases mainly associated with bacteria, such as dental caries, gingivitis and mucositides. Dental caries is undoubtedly a major oral health problem worldwide, with an increasing tendency of incidence. The purpose of this perspective review is to describe the recent progress in the laboratory and clinical use of honey in the prevention of dental caries, with emphasis on the antibacterial and antibiofilm effects of honey. The role of honey in the cariogenic process is also discussed. In addition, the quality of honey and the urgent in vitro evaluation of its antibacterial/antibiofilm properties before clinical use are highlighted. Findings based on data extracted from laboratory studies demonstrate the pronounced antibacterial effect of different honeys against a number of periodontal pathogens, including Streptococcus mutans. Although the promising antibiofilm effects of honey have been reported mainly against S. mutans, these results are limited to very few studies. From a clinical point of view, honey significantly reduces dental plaque; however, it is not superior to the conventional agent. Despite the positive in vitro results, the clinical effectiveness of honey in the prevention of dental caries remains inconclusive since further robust clinical studies are needed.
- [Antimicrobial activity of honey in periodontal disease: a systematic review | Journal of Antimicrobial Chemotherapy | Oxford Academic](https://umf.brandkitapp.com/asset-page/651451-antimicrobial-activity-of-honey-in-periodontal-disease-a-systematic-review-journal-of-antimicrobial-chemotherapy-oxford-academic) : AbstractBackground. Honey has shown positive antimicrobial and anti-inflammatory actions in several dermatological studies; however, it is unclear if it co
- [In-vitro susceptibility of methicillin-resistant Stayphylococcus aureus to honey - PubMed](https://umf.brandkitapp.com/asset-page/651450-in-vitro-susceptibility-of-methicillin-resistant-stayphylococcus-aureus-to-honey-pubmed) : Wound infections caused by methicillin-resistant Staphylococcus aureus (MRSA) is becoming much complicated and costly to treat as antimicrobial resistance is quite common. Twenty five MRSA strains isolated from infected wounds and three ATCC reference strains were evaluated for their susceptibility …
- [Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration - PubMed](https://umf.brandkitapp.com/asset-page/651447-health-benefits-of-manuka-honey-as-an-essential-constituent-for-tissue-regeneration-pubmed) : In addition to bacterial growth inhibition, glyoxal (GO) and MGO from Manuka honey can enhance wound healing and tissue regeneration by their immunomodulatory property. Further studies are needed to provide detailed information about active components of Manuka honey and their potential efficacy in …
- [Antioxidant, Anticancer, Antibacterial, Antibiofilm Properties and Gas Chromatography and Mass Spectrometry Analysis of Manuka Honey: A Nature’s Bioactive Honey](https://umf.brandkitapp.com/asset-page/651161-antioxidant-anticancer-antibacterial-antibiofilm-properties-and-gas-chromatography-and-mass-spectrometry-analysis-of-manuka-honey-a-natureamprsquos-bioactive-honey) : Honey has a history of medical use and is known as bio-alternative therapy. This research assessed the phytochemical and biological activity of the medical grade manuka honey (MH). Gas chromatography–mass spectrometry (GC–MS) was chosen to investigate bioactive compounds of the MH. The DPPH and ABTS free radical scavenging and beta-carotene antioxidant activities as well as the antibacterial and antibiofilm effects against S. aureus, B. subtilis, E. coli and P. aeruginosa were all determined. Furthermore, to gauge anticancer properties of MH, a MTT assay was opted towards three cell lines, including HCT-116 (colon), A549 (lung) and MCF-7 (breast) cancer cells. The GC–MS analysis of the tested MH revealed the identification of various chemical constituents belonging to the fatty acids, phenols, and esters. The MH was found to have higher reducing power activity (DPPH IC50: 7.36; ABTS IC50: 4.49 mg/mL) than the beta-carotene bleaching power (IC50: 37.51 mg/mL). Similarly, the MH was noted to be more active against the planktonic and biofilm of Gram-positive bacteria. Furthermore, a dose-dependent anticancer potential was observed, although a significant anticancer potential was pointed out against the MCF-7 and A549 cell conforming to the IC50 values of 9.05 and 9.37 mg/mL, respectively. This study’s results have highlighted the MH’s chemical composition with significant bioactivities.
- [How to choose Mānuka Honey - YouTube](https://umf.brandkitapp.com/asset-page/558100-how-to-choose-manuka-honey-youtube) : Watch this video to learn how to choose the right Mānuka Honey for your health or others.
## Images
- [WMHD Banner - tagline](https://umf.brandkitapp.com/asset-page/789385-wmhd-banner-tagline) : World Manuka Honey Day banner featuring a bee on a white flower with a soft yellow background. Highlights: One Source. One Standard. The World's Healthiest Honey. 3rd November. UMF logo top-right.
- [WMHD-Social](https://umf.brandkitapp.com/asset-page/789387-wmhd-social) : World Mānuka Honey Day poster featuring a bee on a white blossom, 3rd November. Includes the UMF hex badge (Unique Mānuka Factor) in the top-right, promoting mānuka honey and pollinator health.
- [WMHD Social_Tagline_](https://umf.brandkitapp.com/asset-page/789388-wmhd-social_tagline_) : World Mānuka Honey Day poster: a honeybee on a white flower with the UMF badge. Text reads One Source. One Standard. The World's Healthiest Honey. 3rd November.
- [WMHD Banner](https://umf.brandkitapp.com/asset-page/789386-wmhd-banner) : Banner for World Mānuka Honey Day (Nov 3) showing a bee on a white flower with a UMF hex logo. Promotes UMF-rated Manuka honey and natural floral imagery.
- [J003731 - WMHD Social - 5 Days](https://umf.brandkitapp.com/asset-page/787169-j003731-wmhd-social-5-days) : Countdown graphic for World Manuka Honey Day. Bright orange background with UMF logo, large “DAYS TO GO!” text. Beekeeper in protective suit tending a yellow hive, bees buzzing around. Includes “World Manuka Honey Day, 3rd November.”
- [J003731 - WMHD Social - 4 Days](https://umf.brandkitapp.com/asset-page/787164-j003731-wmhd-social-4-days) : UMF logo on an orange gradient banner. Text: “DAYS TO GO!” and “World Manuka Honey Day – 3rd November.” Stack of beehives in a grassy, hilly landscape framed by a geometric cutout. Promo image for Manuka honey lovers.
- [J003731 - WMHD Social - 3 Days](https://umf.brandkitapp.com/asset-page/787165-j003731-wmhd-social-3-days) : Countdown graphic for World Mānuka Honey Day. Yellow backdrop with UMF logo, honey dripping from a wooden dipper, and bold “DAYS TO GO!” alongside “World Mānuka Honey Day – 3rd November.”
- [J003731 - WMHD Social - 1 Day](https://umf.brandkitapp.com/asset-page/787166-j003731-wmhd-social-1-day) : UMF logo with a World Manuka Honey Day promo. A bee on a white flower sits on a green gradient background, with bold text “DAY TO GO!” and “World Manuka Honey Day – 3rd November” graphic.
- [J003731 - WMHD Social - 7 Days](https://umf.brandkitapp.com/asset-page/787167-j003731-wmhd-social-7-days) : Promo poster for World Manuka Honey Day. Yellow gradient background, UMF logo, bold “DAYS TO GO!”, bee on a white flower through a diagonal cutout, with text “World Manuka Honey Day” and “3rd November.”
- [J003731 - WMHD Social - 6 Days](https://umf.brandkitapp.com/asset-page/787168-j003731-wmhd-social-6-days) : UMF logo on olive gradient background. A large honeycomb-textured number 6 with dripping honey, symbolizing a countdown to World Mānuka Honey Day. Text reads “DAYS TO GO!” and “World Mānuka Honey Day – 3rd November.”
- [J003731 - WMHD Social - 2 Days](https://umf.brandkitapp.com/asset-page/787170-j003731-wmhd-social-2-days) : Countdown graphic for World Mānuka Honey Day. UMF logo on an orange gradient background with “DAYS TO GO!” A woman outdoors drizzles honey over a berry-granola bowl. Date: 3rd November.
- [22](https://umf.brandkitapp.com/asset-page/777010-22) : Beekeeper in gloves holds a honeycomb frame covered with bees in a sunlit field. Outdoor beekeeping scene with a logo in the corner, highlighting manuka honey and bee colony inspection.
- [Haddrell's Queen Bee Rearer 5](https://umf.brandkitapp.com/asset-page/777028-haddrells-queen-bee-rearer-5) : Beekeeper in protective gear inspects a hive, handling honeycomb frames as bees buzz around. Close-up of hands, hive bars, and frame insertion — a routine apiary check for healthy bees and honey production.
- [Golden beekeeper](https://umf.brandkitapp.com/asset-page/777029-golden-beekeeper) : Beekeeper in a protective suit holds a honeycomb frame teeming with bees in a sunlit field, illustrating beekeeping, honey production, and honeycomb inspection.
- [gerardo-covarrubias-tJiWEZjM7Eo-unsplash](https://umf.brandkitapp.com/asset-page/777030-gerardo-covarrubias-tjiwezjm7eo-unsplash) : Two honeycomb pieces on a dark cutting board set on a teal surface. A yellow pot and white napkin sit nearby. Natural honeycomb with visible hexagonal cells, ready to eat.
- [shutterstock_269094923](https://umf.brandkitapp.com/asset-page/777026-shutterstock_269094923) : Close-up of white manuka blossoms (Leptospermum scoparium) with pink center stamens and yellow-green leaves. Soft, blurred background. Great for Manuka honey imagery, nectar, pollination, and New Zealand flora.
- [shutterstock_1061762705](https://umf.brandkitapp.com/asset-page/777025-shutterstock_1061762705) : Close-up of a glass jar of golden honey with a wooden spoon dipped in. Rich amber, glossy honey swirls on a burlap surface—natural, smooth, and inviting, perfect for Manuka honey branding.
- [shutterstock_1116935243](https://umf.brandkitapp.com/asset-page/777024-shutterstock_1116935243) : Top-down view of an open honey jar with a wooden honey dipper, thick golden honey, and a yellow lid nearby on a bright yellow gingham tablecloth.
- [shutterstock_1147042979](https://umf.brandkitapp.com/asset-page/777023-shutterstock_1147042979) : Golden honey drips from a wooden honey dipper onto a honeycomb background, with white manuka flowers in the corner. A simple, appealing image of Manuka honey.
- [shutterstock_2139092985](https://umf.brandkitapp.com/asset-page/777022-shutterstock_2139092985) : Hand holding slender stems with tiny white blossoms; delicate, minimal botanical image against a pale background. Wildflowers, floral, nature photography.
- [shutterstock_2244250173](https://umf.brandkitapp.com/asset-page/777021-shutterstock_2244250173) : Close-up of honeycomb on a plate with dripping honey, amber cells visible. A small sprig of white flowers sits beside it against a green, blurred background. Natural honey, raw honeycomb - great for Manuka honey branding.
- [hives](https://umf.brandkitapp.com/asset-page/777027-hives) : Bee Hives beside native Kanuka bush in Summer. — Apiary in a grassy field with stacked wooden beehives and metal roofs. Colorful hive stripes. Surrounded by scrubby hills and a blue sky—a natural honey production landscape.
- [shutterstock_2264624131](https://umf.brandkitapp.com/asset-page/777020-shutterstock_2264624131) : Close-up of small pink-white blossoms on slender evergreen heather branches; tiny needle leaves with a soft green bokeh background, spring garden flora.
- [shutterstock_2305675199](https://umf.brandkitapp.com/asset-page/777019-shutterstock_2305675199) : Open jar of rich Manuka honey with a wooden honey dipper, amber honey dripping on a white background. Perfect for flavor, tea, or cooking; a clean, enticing shot for Unique Mānuka Factor Honey.
- [shutterstock_2324557861](https://umf.brandkitapp.com/asset-page/777018-shutterstock_2324557861) : Jar of golden honey with a wooden spoon resting inside. Rich amber honey on a clean white background, ready to drizzle.
- [shutterstock_2335067319](https://umf.brandkitapp.com/asset-page/777017-shutterstock_2335067319) : Hillside covered in blooming manuka (tea tree) shrubs with white pom-pom flowers; rolling countryside in the distance. A natural NZ scene perfect for Manuka honey branding.
- [shutterstock_2336223855](https://umf.brandkitapp.com/asset-page/777016-shutterstock_2336223855) : Close-up of manuka flowers on a woody branch: clusters of small white blossoms with dark centers, slender green leaves. A classic image for manuka honey branding.
- [shutterstock_2422053373](https://umf.brandkitapp.com/asset-page/777015-shutterstock_2422053373) : Golden honey drips from a wooden honey dipper into a small jar on a rustic wood surface. Dark backdrop with soft blossoms, evoking natural Manuka honey and its pure sweetness.
- [shutterstock_2433701849](https://umf.brandkitapp.com/asset-page/777014-shutterstock_2433701849) : Golden Manuka honey pours onto a honeycomb in a wooden dish, forming a glossy, rich pool. A natural, delicious treat.
- [shutterstock_2467369147](https://umf.brandkitapp.com/asset-page/777013-shutterstock_2467369147) : A lush flowering shrub in full bloom, covered with tiny white blossoms along arching branches. Green leaves peek through, creating a bright spring garden scene.
- [Testtubes](https://umf.brandkitapp.com/asset-page/777012-testtubes) : Close-up of a pipette releasing golden Manuka honey into glass test tubes in a lab, with warm amber tones highlighting quality testing and research.
- [two_people_celebrating](https://umf.brandkitapp.com/asset-page/777011-two_people_celebrating) : Two friends with backpacks raise their arms in joy at a scenic overlook. They stand on a hillside among green shrubs, with distant cliffs and a bright outdoor nature moment.
- [mod6](https://umf.brandkitapp.com/asset-page/777006-mod6) : Close-up of a jar labeled Mānuka Honey (UMF 10+) from New Zealand. Golden honey with the lid off sits beside slices of toast on a bright kitchen counter, with a blurred background.
- [flower](https://umf.brandkitapp.com/asset-page/777007-flower) : Close-up of a honey bee on white blossoms with reddish centers. A bee gathers nectar from a flowering shrub, green blurred background. Highlights pollination, spring bloom, bees, and honey production.
- [215](https://umf.brandkitapp.com/asset-page/777008-215) : Close-up of honey bees on a honeycomb. Worker bees cluster around hexagonal cells, collecting nectar and pollen. Golden tones highlight fuzzy bodies and clear wings in a busy pollination moment.
- [188ddb93dda3ab74328b422e7626a64d8ccaba15](https://umf.brandkitapp.com/asset-page/777009-188ddb93dda3ab74328b422e7626a64d8ccaba15) : Apiary scene with rows of colorful beehives on a sunny field. Beekeepers in protective suits inspect the hives as dust rises. Forest and mountains in the background—a rural honey production setting.
- [maori manuka leaes](https://umf.brandkitapp.com/asset-page/776997-maori-manuka-leaes) : Close-up of weathered hands harvesting a green sprig with tiny needle-like leaves. Dirt on hands, outdoors, capturing a fresh herb plant being gathered.
- [manuka-tree-flowering](https://umf.brandkitapp.com/asset-page/776998-manuka-tree-flowering) : Dense evergreen shrub with small leaves and abundant white blossoms along the branches. Ideal as a garden hedge or feature plant; spring bloom attracts pollinators.
- [manuka-honey-167497019](https://umf.brandkitapp.com/asset-page/776999-manuka-honey-167497019) : Bright, smiling woman enjoying a honey skincare routine. She applies amber honey to her shoulder with a spoon over a bowl of honey, conveying natural self-care, spa vibes, and wellness.
- [manuka spoon](https://umf.brandkitapp.com/asset-page/777000-manuka-spoon) : Golden honey in a wooden scoop rests among white manuka flowers on green foliage—natural nectar, pure Mānuka honey scene.
- [shutterstock_2492066815](https://umf.brandkitapp.com/asset-page/777001-shutterstock_2492066815) : Two senior women tasting UMF mānuka honey from a spoon in a bright indoor setting. Close-up of one savoring the sample while the other watches, highlighting flavor testing and quality assessment.
- [shutterstock_2433701849](https://umf.brandkitapp.com/asset-page/777002-shutterstock_2433701849) : Close-up of golden manuka honey pouring onto a wooden dish beside a honeycomb. Thick, amber honey pools around the comb, highlighting natural texture, purity, and premium quality of Manuka honey.
- [shutterstock_2422053373](https://umf.brandkitapp.com/asset-page/777003-shutterstock_2422053373) : Amber Manuka honey drips from a wooden honey dipper into a small glass bowl atop a rustic wooden surface; a dark blurred background with hints of blossoms adds contrast.
- [shutterstock_2305675199](https://umf.brandkitapp.com/asset-page/777004-shutterstock_2305675199) : Jar of golden mānuka honey with a wooden honey dipper resting beside it on a white background; honey drips and two small droplets nearby. Clean, minimalist shot highlighting premium, natural honey.
- [MWC_NZStory-honey-12-NZTE Honey2806](https://umf.brandkitapp.com/asset-page/777005-mwc_nzstory-honey-12-nzte-honey2806) : Golden honeycomb pieces on a rustic wooden surface, framed by small white blossoms. Rich amber honey and natural beekeeping imagery, ideal for mānuka honey branding.
- [2012-08-16 Notice on Sugars](https://umf.brandkitapp.com/asset-page/758837-2012-08-16-notice-on-sugars) : Official notice from Unique Mānuka Factor Honey Association, dated August 16, 2013, regarding sugar testing for UMF honey. Highlights include licensing, testing requirements, and honey standards, emphasizing quality assurance and regulatory compliance.
- [Sustainable-Practices](https://umf.brandkitapp.com/asset-page/670174-sustainable-practices) 
- [shutterstock_2264624131](https://umf.brandkitapp.com/asset-page/658259-shutterstock_2264624131) 
- [shutterstock_2336223855](https://umf.brandkitapp.com/asset-page/658258-shutterstock_2336223855) 
- [shutterstock_2335067319](https://umf.brandkitapp.com/asset-page/658257-shutterstock_2335067319) 
- [shutterstock_2433701849](https://umf.brandkitapp.com/asset-page/658256-shutterstock_2433701849) 
- [shutterstock_2324557861](https://umf.brandkitapp.com/asset-page/658255-shutterstock_2324557861) 
- [shutterstock_2305675199](https://umf.brandkitapp.com/asset-page/658254-shutterstock_2305675199) 
- [shutterstock_2422053373](https://umf.brandkitapp.com/asset-page/658253-shutterstock_2422053373) 
- [Market Access](https://umf.brandkitapp.com/asset-page/654130-market-access) 
- [Insights](https://umf.brandkitapp.com/asset-page/654129-insights) 
- [Benefits Post - Square](https://umf.brandkitapp.com/asset-page/654128-benefits-post-square) 
- [UMF Logo Certified](https://umf.brandkitapp.com/asset-page/652679-umf-logo-certified) 
- [UMF Logo Certified](https://umf.brandkitapp.com/asset-page/652677-umf-logo-certified) 
- [UMF Quality Mark Colour RGB](https://umf.brandkitapp.com/asset-page/652675-umf-quality-mark-colour-rgb) 
- [UMF Quality Mark Reverse RGB](https://umf.brandkitapp.com/asset-page/652676-umf-quality-mark-reverse-rgb) 
- [Manuka Tree](https://umf.brandkitapp.com/asset-page/651100-manuka-tree) 
- [Manuka Bush](https://umf.brandkitapp.com/asset-page/651101-manuka-bush) 
- [Manuka Honeycomb](https://umf.brandkitapp.com/asset-page/651098-manuka-honeycomb) 
- [Honey Breakfast](https://umf.brandkitapp.com/asset-page/651099-honey-breakfast) 
- [Bee on tree](https://umf.brandkitapp.com/asset-page/651091-bee-on-tree) 
- [Bee on Flower](https://umf.brandkitapp.com/asset-page/651092-bee-on-flower) 
- [Wild Manuka](https://umf.brandkitapp.com/asset-page/651093-wild-manuka) 
- [Man](https://umf.brandkitapp.com/asset-page/651094-man) 
- [Friends](https://umf.brandkitapp.com/asset-page/651095-friends) 
- [People](https://umf.brandkitapp.com/asset-page/651096-people) 
- [Bee on Manuka Flower](https://umf.brandkitapp.com/asset-page/651097-bee-on-manuka-flower) 
- [UMF_Double pager_4_Indonesian](https://umf.brandkitapp.com/asset-page/651090-umf_double-pager_4_indonesian) 
- [UMF Double pager 4 MAR23 DEDE](https://umf.brandkitapp.com/asset-page/651086-umf-double-pager-4-mar23-dede) 
- [Purity](https://umf.brandkitapp.com/asset-page/650696-purity) 
- [Traceability](https://umf.brandkitapp.com/asset-page/650694-traceability) 
- [Bioactive - A](https://umf.brandkitapp.com/asset-page/650707-bioactive-a) 
- [Bioactive - B](https://umf.brandkitapp.com/asset-page/650706-bioactive-b) 
- [Bioactive](https://umf.brandkitapp.com/asset-page/650705-bioactive) 
- [Certified](https://umf.brandkitapp.com/asset-page/650704-certified) 
- [Food Safety](https://umf.brandkitapp.com/asset-page/650703-food-safety) 
- [ID](https://umf.brandkitapp.com/asset-page/650702-id) 
- [Immune Health](https://umf.brandkitapp.com/asset-page/650701-immune-health) 
- [Longevity](https://umf.brandkitapp.com/asset-page/650700-longevity) 
- [New Zealand](https://umf.brandkitapp.com/asset-page/650699-new-zealand) 
- [Potency - A](https://umf.brandkitapp.com/asset-page/650698-potency-a) 
- [Potency - B](https://umf.brandkitapp.com/asset-page/650697-potency-b) 
- [Quality](https://umf.brandkitapp.com/asset-page/650695-quality) 
- [90 Natural Components](https://umf.brandkitapp.com/asset-page/650717-90-natural-components) 
- [2300 Natural Components](https://umf.brandkitapp.com/asset-page/650716-2300-natural-components) 
- [Anti-bacterial](https://umf.brandkitapp.com/asset-page/650715-anti-bacterial) 
- [Anti-inflamatory - 2](https://umf.brandkitapp.com/asset-page/650714-anti-inflamatory-2) 
- [Anti-inflamatory](https://umf.brandkitapp.com/asset-page/650713-anti-inflamatory) 
- [Antioxidant - A](https://umf.brandkitapp.com/asset-page/650712-antioxidant-a) 
- [Antioxidant - A2](https://umf.brandkitapp.com/asset-page/650711-antioxidant-a2) 
- [Antioxidant - B](https://umf.brandkitapp.com/asset-page/650710-antioxidant-b) 
- [Antioxidant - B2](https://umf.brandkitapp.com/asset-page/650709-antioxidant-b2) 
- [Authenticity](https://umf.brandkitapp.com/asset-page/650708-authenticity) 
- [J002587 - Benefits Post - 1a](https://umf.brandkitapp.com/asset-page/650688-j002587-benefits-post-1a) 
- [J002587 - Benefits Post - 1b](https://umf.brandkitapp.com/asset-page/650687-j002587-benefits-post-1b) 
- [J002587 - Benefits Post - 2a](https://umf.brandkitapp.com/asset-page/650686-j002587-benefits-post-2a) 
- [J002587 - Benefits Post - 2b](https://umf.brandkitapp.com/asset-page/650685-j002587-benefits-post-2b) 
- [J002587 - Benefits Post - 3a](https://umf.brandkitapp.com/asset-page/650684-j002587-benefits-post-3a) 
- [J002587 - Benefits Post - 3b](https://umf.brandkitapp.com/asset-page/650683-j002587-benefits-post-3b) 
- [J002587 - Benefits Post - 4a](https://umf.brandkitapp.com/asset-page/650682-j002587-benefits-post-4a) 
- [J002587 - Benefits Post - 4b](https://umf.brandkitapp.com/asset-page/650681-j002587-benefits-post-4b) 
- [J002587 - Benefits Post - 5a](https://umf.brandkitapp.com/asset-page/650680-j002587-benefits-post-5a) 
- [J002587 - Benefits Post - 5b](https://umf.brandkitapp.com/asset-page/650679-j002587-benefits-post-5b) 
- [J002587 - Benefits Post](https://umf.brandkitapp.com/asset-page/650678-j002587-benefits-post) 
- [UMF - Logo_Certified](https://umf.brandkitapp.com/asset-page/650675-umf-logo_certified) 
- [umf-logo](https://umf.brandkitapp.com/asset-page/558097-umf-logo) 
- [umf-icon](https://umf.brandkitapp.com/asset-page/558098-umf-icon) 
- [Honeycomb](https://umf.brandkitapp.com/asset-page/558096-honeycomb) 
## Posts
- [The Gut Health Benefits of Manuka Honey & Why Certified New Zealand Manuka Honey is Essential](https://umf.brandkitapp.com/asset-page/710818-the-gut-health-benefits-of-manuka-honey-why-certified-new-zealand-manuka-honey-is-essential)
## Videos
- [9. VIDEO 9 Cutdown_V1](https://umf.brandkitapp.com/asset-page/697059-9-video-9-cutdown_v1) 
- [3. VIDEO 3 Cutdown_V1](https://umf.brandkitapp.com/asset-page/697053-3-video-3-cutdown_v1) 
- [6.1 VIDEO 6 Cutdown 1_V1](https://umf.brandkitapp.com/asset-page/697058-61-video-6-cutdown-1_v1) 
- [4. VIDEO 4 Cutdown_V1](https://umf.brandkitapp.com/asset-page/697052-4-video-4-cutdown_v1) 
- [5. VIDEO 5 Cutdown_V1](https://umf.brandkitapp.com/asset-page/697051-5-video-5-cutdown_v1) 
- [1.2 VIDEO 1 Cutdown 2_V1](https://umf.brandkitapp.com/asset-page/697050-12-video-1-cutdown-2_v1) 
- [1.3 VIDEO 1 Cutdown 3_V1](https://umf.brandkitapp.com/asset-page/697049-13-video-1-cutdown-3_v1) 
- [2.1 VIDEO 2 Cutdown 1_V1](https://umf.brandkitapp.com/asset-page/697048-21-video-2-cutdown-1_v1) 
- [6.2 VIDEO 6 Cutdown 2_V1](https://umf.brandkitapp.com/asset-page/697057-62-video-6-cutdown-2_v1) 
- [7. VIDEO 7 Cutdown_V1](https://umf.brandkitapp.com/asset-page/697056-7-video-7-cutdown_v1) 
- [2.2 VIDEO 2 Cutdown 2_V1](https://umf.brandkitapp.com/asset-page/697047-22-video-2-cutdown-2_v1) 
- [1.1 VIDEO 1 Cutdown 1_V1](https://umf.brandkitapp.com/asset-page/697046-11-video-1-cutdown-1_v1) 
- [8.1 VIDEO 8 Cutdown 1_V1](https://umf.brandkitapp.com/asset-page/697055-81-video-8-cutdown-1_v1) 
- [8.2 VIDEO 8 Cutdown 2_V1](https://umf.brandkitapp.com/asset-page/697054-82-video-8-cutdown-2_v1) 
- [2. UMF VIDEO 2 - MASTER](https://umf.brandkitapp.com/asset-page/650728-2-umf-video-2-master) 
- [1. UMF VIDEO 1 - MASTER](https://umf.brandkitapp.com/asset-page/650729-1-umf-video-1-master) 
- [9. UMF VIDEO 9 - MASTER](https://umf.brandkitapp.com/asset-page/650721-9-umf-video-9-master) 
- [10. UMF 9-PART SERIES TRAILER - MASTER](https://umf.brandkitapp.com/asset-page/650720-10-umf-9-part-series-trailer-master) 
- [8. UMF VIDEO 8 - MASTER](https://umf.brandkitapp.com/asset-page/650722-8-umf-video-8-master) 
- [7. UMF VIDEO 7 - MASTER](https://umf.brandkitapp.com/asset-page/650723-7-umf-video-7-master) 
- [3. UMF VIDEO 3 - MASTER](https://umf.brandkitapp.com/asset-page/650727-3-umf-video-3-master) 
- [4. UMF VIDEO 4 - MASTER](https://umf.brandkitapp.com/asset-page/650726-4-umf-video-4-master) 
- [5. UMF VIDEO 5 - MASTER](https://umf.brandkitapp.com/asset-page/650725-5-umf-video-5-master) 
- [6. UMF VIDEO 6 - MASTER](https://umf.brandkitapp.com/asset-page/650724-6-umf-video-6-master) 